Costa L

No ORCID on file · 6 papers in corpus · active 2020-2025

Study types

  • article 1
  • other 1
  • preprint 1
  • rct 1

Condition tags

  • endometriosis 4
  • infertility 1
  • adenomyosis 1
rct 2025
Ultrasound-guided ethanol sclerotherapy versus laparoscopic surgery for endometriomas: a randomized clinical trial in a real-world setting
Archives of gynecology and obstetrics ·doi:10.1007/s00404-025-08205-1

PURPOSE: To compare the efficacy of ultrasound-guided alcohol sclerotherapy versus laparoscopic cystectomy for the management of ovarian endometriomas, focusing on complications, recurrence, pain relief, and healthcare costs. METHODS: We c…

preprint 2025
Ultrasound-Guided Ethanol Sclerotherapy versus Laparoscopic Surgery for Endometriomas: As-Treated Analysis of a Pragmatic Randomized Clinical Trial
·doi:10.22541/au.174616570.09691073/v1

Objective: To compare the efficacy of ultrasound-guided alcohol sclerotherapy versus laparoscopic cystectomy for the management of ovarian endometriomas, focusing on complications, recurrence, pain relief, and healthcare costs. Design: Mult…

article 2022
Increased expression of NLRP3 inflammasome components in granulosa cells and follicular fluid interleukin(IL)-1beta and IL-18 levels in fresh IVF/ICSI cycles in women with endometriosis
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-022-02662-2

The inflammasomes are a family of recently described multi-protein cytoplasmic sensors that orchestrate the inflammatory response and participate in a variety of inflammatory conditions. We hypothesized that the activation of pyrin domain‑c…

other 2021
Concentrations of the endocannabinoid N-arachidonoylethanolamine in the follicular fluid of women with endometriosis: the role of M1 polarised macrophages
Reproduction, fertility, and development ·doi:10.1071/RD20247

Although N-arachidonoylethanolamine (AEA; also known as anandamide) is present in human follicular fluid (FF), its regulation remains unknown. Therefore, the aims of the present study were to: (1) investigate the relationships between FF AE…

2021
Low Doses of Resveratrol Protect Human Granulosa Cells from Induced-Oxidative Stress.
Antioxidants (Basel, Switzerland) ·doi:10.3390/antiox10040561

Resveratrol is a phytoalexin present in plant-derived foods, including grape's skin, cocoa, and peanuts. Evidence suggests that it has beneficial effects on human health because of its antioxidant properties. However, there is limited knowl…

2020
The endocannabinoid 2-arachidonoylglycerol promotes endoplasmic reticulum stress in placental cells.
Reproduction (Cambridge, England) ·doi:10.1530/rep-19-0539

Proliferation, differentiation and apoptosis of trophoblast cells are required for normal placental development. Impairment of those processes may lead to pregnancy-related diseases. Disruption of endoplasmic reticulum (ER) homeostasis has …