Raul Cavalcante Maranhão

No ORCID on file · 4 papers in corpus · active 2016-2023

Study types

  • article 4

Condition tags

  • endometriosis 4
  • dysmenorrhea 1
  • chronic_pelvic_pain 1
  • bowel_endometriosis 1
  • dyspareunia 1
article 2023
Pilot study of treatment of patients with deep infiltrative endometriosis with methotrexate carried in lipid nanoparticles
Archives of gynecology and obstetrics ·doi:10.1007/s00404-023-07246-8

OBJECTIVE: Previously, lipid nanoparticles (LDE) injected in women with endometriosis were shown to concentrate in the lesions. Here, the safety and feasibility of LDE carrying methotrexate (MTX) to treat deep infiltrating endometriosis was…

article 2021
Treatment of Deep Infiltrative Endometriosis with Methotrexate Carried in Lipid Core Nanoparticles (LDE): A Pilot Study
·doi:10.1016/j.jmig.2021.09.436
article 2019
Nanotechnology for the treatment of deep endometriosis: uptake of lipid core nanoparticles by LDL receptors in endometriotic foci
Clinics (Sao Paulo, Brazil) ·doi:10.6061/clinics/2019/e989

OBJECTIVE: Rapidly dividing cells in multiple types of cancer and inflammatory diseases undergo high low density lipoprotein (LDL) uptake for membrane synthesis, and coupling an LDL-like nanoemulsion, containing lipid nanoparticles (LDE) to…

article 2016
mRNA levels of low-density lipoprotein receptors are overexpressed in the foci of deep bowel endometriosis
Human Reproduction ·doi:10.1093/humrep/dew303

STUDY QUESTION: Is mRNA expression of LDL receptors altered in deep bowel endometriotic foci? SUMMARY ANSWER: mRNA expression of LDL receptors is up-regulated in deep bowel endometriotic foci of patients with endometriosis. WHAT IS KNOWN AL…