Lichun Weng

No ORCID on file · 6 papers in corpus · active 2020-2022

Study types

  • article 5
  • preprint 1

Condition tags

  • endometriosis 6
  • dysmenorrhea 1
  • chronic_pelvic_pain 1
  • infertility 1
  • endometrioma 1
article 2022
Downregulating HK2 inhibits proliferation of endometrial stromal cells through a noncanonical pathway involving phosphorylation of signal transducer and activator of transcription 1 in endometriosis
Biology of reproduction ·doi:10.1093/biolre/ioac081

BACKGROUND: Endometriosis is a benign gynecologic disease that causes chronic pelvic pain, dysmenorrhea and infertility and shares several characteristics with malignant tumors, afflicting women of reproductive age. Hexokinase 2 plays an es…

article 2022
Hypoxia-hindered methylation of PTGIS in endometrial stromal cells accelerates endometriosis progression by inducing CD16- NK-cell differentiation
Experimental & molecular medicine ·doi:10.1038/s12276-022-00793-1

Prostacyclin (PGI2) plays key roles in shaping the immune microenvironment and modulating vasodilation, whereas its contribution to endometriosis (EMs) remains largely unclear. Our study suggested that prostacyclin synthase (PTGIS)-dependen…

article 2022
PrPC Promotes Endometriosis Progression by Reprogramming Cholesterol Metabolism and Estrogen Biosynthesis of Endometrial Stromal Cells through PPARα Pathway
International journal of biological sciences ·doi:10.7150/ijbs.68015

Endometriosis (EMs) is characterized as an estrogen-dependent disease. Whereas, the underlying mechanism for activated estrogen biosynthesis in EMs lesions is largely unknown. We analyzed cholesterol metabolism and estrogen biosynthesis con…

preprint 2021
Down-Regulating Hexokinase 2 Inhibits Proliferation of Endometrial Stromal Cells Through a Noncanonical Pathway Involving Phosphorylated-STAT1 in Endometriosis
·doi:10.21203/rs.3.rs-845266/v1
article 2021
SMURF1-mediated ubiquitylation of SHP-1 promotes cell proliferation and invasion of endometrial stromal cells in endometriosis
Annals of translational medicine ·doi:10.21037/atm-20-2897

BACKGROUND: Endometriosis is a widespread benign gynecological disorder. The signal transducer and activator of transcription 3 (STAT3) signaling pathway plays an important role in the pathogenesis of endometriosis through regulating prolif…

article 2020
Estrogen-regulated CD200 inhibits macrophage phagocytosis in endometriosis
Journal of reproductive immunology ·doi:10.1016/j.jri.2020.103090