Wang J

BACKGROUND: Ovarian endometriosis cysts are common gynecological conditions and are mostly benign. While many cysts resolve spontaneously, symptomatic or persistent cysts often require interventions. Laparoscopic cystectomy and ultrasound-g…

BackgroundAssessing plasma volume is important in the management and treatment of severe acute pancreatitis (SAP). Although it is an easy and rapid method for estimating the plasma volume, the association between estimated plasma volume sta…

BackgroundCarotenoids, known for their antioxidant properties and potential health benefits, have attracted considerable attention. Nonetheless, the association between carotenoid levels and gallstone prevalence has not been adequately expl…

This study aims to explore the association between stress coping and primary dysmenorrhea among Chinese female adolescent students. A two-step random, stratified, cluster sampling method was employed to assess the health status of female ad…

BackgroundInfertility in women of reproductive age is a major worldwide health problem. Oxidative stress, inflammatory responses, and dysregulation of lipid metabolism are among the factors that contribute to female infertility. The ratio o…

Women's reproductive health plays a pivotal role in both longevity and the aging process. We conduct Mendelian randomization (MR) and observational analyses to investigate these relationships. Univariate MR analyses reveal that older age at…

PurposeThis study aimed to monitor the expression of B-cell translocation gene 2 (BTG2) in granulosa cells of patients undergoing IVF/ICSI with respect blastocyst quality outcomes.MethodsWe recruited 181 women undergoing IVF/ICSI cycles for…

PURPOSE: To evaluate the impact of poor ovarian response (POR) on live birth outcomes in endometriosis patients undergoing IVF/ICSI-ET, despite the expected association between reduced oocyte yield and poorer prognosis. METHODS: Patients w…

RESEARCH QUESTION: Can bioinformatics-driven identification of hub genes in granulosa cells be used to predict oocyte developmental potential in patients with endometriosis (EMS)-related infertility? DESIGN: This was an exploratory cohort …

Endometriosis is a common gynecological condition. However, endometriosis-associated malignancies occur in up to 1% of women with endometriosis. Most cases of endometriosis-associated malignancy occur in the ovary, whereas 20% of cases occu…

Various pathologies, environmental factors, and medications can cause anal distension. Sacrococcygeal chordoma is a rare tumor originating from the remnants of the primitive spinal cord. Nonetheless, only a few case reports of anal swelling…

IntroductionAbdominal ectopic pregnancies(APs) is a rare type of ectopic pregnancy, most commonly implanting in the rectouterine pouch. The treatment methods include surgical treatment and drug therapy. In the surgical treatment of ectopic …

BACKGROUND: Low-grade endometrial stromal sarcoma (LGESS) with pulmonary metastasis is a rare malignant mesenchymal tumor. LGESS is composed of cells resembling proliferative endometrial stromal cells. It grows slowly and has a favorable pr…

RESEARCH QUESTION: Do mast cells play a role in the pathogenesis of endometriosis and, if so, what is the mechanism of action? DESIGN: The study included 18 women with ovarian endometriosis and 13 women without endometriosis. Primary endom…

Endometriosis is common and poses significant morbidity of lasting impact to young, pre-menopausal women, while ovarian cancer is a lethal gynecologic condition. Both conditions need better treatment. The human omentum is an apron of adipos…

Ovarian cancer, particularly epithelial ovarian cancer (EOC), is the most aggressive and lethal gynecologic malignancy, necessitating the development of innovative and potent therapies to improve its prognosis. Human polo-like kinase 1 (PLK…

OBJECTIVE: This study aims to evaluate the efficacy and feasibility of hysteroscopic Mirena suture fixation as a therapeutic approach for adenomyosis. METHODS: A retrospective analysis was conducted on the clinical data of 42 patients diag…

Objective: To compare the efficacy of dienogest (DNG) and levonorgestrel-releasing intrauterine system (LNG-IUS) in the treatment of intrinsic and extrinsic subtypes of adenomyosis. Methods: Totally 232 patients were enrolled in the study w…

BackgroundOocyte vitrification, a widely utilized assisted reproductive technology for fertility preservation, can address emergencies arising from the unavailability of sperm from the male partner on the day of oocyte retrieval. However, t…

Curcumin, the principal bioactive compound derived from turmeric, possesses a wide range of therapeutic properties such as anti-inflammatory, antioxidant, and wound-healing properties. Recent studies suggest that curcumin may alleviate HMGB…

Adenomyosis remains a challenging gynecological disorder to investigate due to the absence of in vitro models that accurately replicate endometrial tissue dynamics across the menstrual cycle. To address this gap, we established an endometri…

Organoids are rapidly self-organizing 3D in vitro cultures derived from pluripotent stem cells (PSCs) or adult stem cells (ASCs) that possess disease-like characteristics with high success rates. Due to their ability to retain tissue struct…

BACKGROUND: Extrinsic adenomyosis exhibits heterogeneous clinical symptoms, with pain being more commonly reported. The relationship between magnetic resonance imaging (MRI) feature and symptom remains unclear. OBJECTIVE: To evaluate the p…

Emerging evidence suggests that microbiota dysbiosis plays a critical role in the pathogenesis of endometrial cancer (EC), a leading cause of cancer-related deaths in women globally. However, few studies have simultaneously examined both th…

BackgroundMore than 500 patients have received cryopreserved ovarian tissue transplantation (OTT) worldwide, resulting in over 200 live births. Although guidelines recognize OTT as an effective fertility preservation method, there is no con…