Moley KH

No ORCID on file · 11 papers in corpus · active 2005-2024

Study types

  • other 4
  • review 1

Condition tags

  • endometriosis 5
  • infertility 1
other 2024
A GREB1-steroid receptor feedforward mechanism governs differential GREB1 action in endometrial function and endometriosis
Nature communications ·doi:10.1038/s41467-024-46180-4

Cellular responses to the steroid hormones, estrogen (E2), and progesterone (P4) are governed by their cognate receptor's transcriptional output. However, the feed-forward mechanisms that shape cell-type-specific transcriptional fulcrums fo…

2016
Diet-induced obesity impairs endometrial stromal cell decidualization: a potential role for impaired autophagy.
Human reproduction (Oxford, England) ·doi:10.1093/humrep/dew048

Study questionWhat effect does diet-induced obesity have on endometrial stromal cell (ESC) decidualization?Summary answerDiet-induced obesity impairs ESC decidualization.What is known alreadyDecidualization is important for successful impla…

other 2011
Adiponectin and adiponectin receptors in the mouse preimplantation embryo and uterus
Human Reproduction ·doi:10.1093/humrep/deq292

BACKGROUND: Adiponectin (Adipoq), a protein secreted by adipocytes in inverse proportion to the adipose mass present, modulates energy homeostasis and increases insulin sensitivity. Tissue Adipoq signaling decreases in settings of maternal …

other 2011
Associations between free fatty acids, cumulus oocyte complex morphology and ovarian function during in vitro fertilization
Fertility and sterility ·doi:10.1016/j.fertnstert.2011.01.154

OBJECTIVE: To determine if follicular free fatty acid (FFA) levels are associated with cumulus oocyte complex (COC) morphology. DESIGN: Prospective cohort study. SETTING: University in vitro fertilization (IVF) practice. PATIENT(S): A to…

other 2011
Elevated serum α-linolenic acid levels are associated with decreased chance of pregnancy after in vitro fertilization
Fertility and sterility ·doi:10.1016/j.fertnstert.2011.07.1115

OBJECTIVE: To analyze relationships between serum free fatty acid (FFA) concentrations and pregnancy. DESIGN: Prospective cohort. SETTING: University hospital. PATIENT(S): Ninety-one women undergoing IVF. INTERVENTION(S): Serum was anal…

2011
Polycystic ovary syndrome and maternal obesity affect oocyte size in in vitro fertilization/intracytoplasmic sperm injection cycles.
Fertility and sterility ·doi:10.1016/j.fertnstert.2010.10.026

To determine the impact of maternal metabolic state on oocyte development in women undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI), we retrospectively analyzed a cohort of women with PCOS undergoing IVF/ICSI fr…

review 2011
Sex Steroid Hormones and Reproductive Disorders
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719111405068

The role of sex steroid hormones in reproductive function in women is well established. However, in the last two decades it has been shown that receptors for estrogens, progesterone and androgens are expressed in non reproductive tissue /or…

2011
Smaller fetal size in singletons after infertility therapies: the influence of technology and the underlying infertility.
Fertility and sterility ·doi:10.1016/j.fertnstert.2011.08.038

ObjectiveTo determine whether fetal size differences exist between matched fertile and infertile women and among women with infertility achieving pregnancy through various treatment modalities.DesignRetrospective cohort study with propensit…

2009
Facilitative glucose transporter type 1 is differentially regulated by progesterone and estrogen in murine and human endometrial stromal cells.
Endocrinology ·doi:10.1210/en.2008-1081

Embryo implantation is a highly synchronized event between an activated blastocyst and a receptive endometrium. The success of this process relies on the dynamic interplay of estrogen (E(2)) and progesterone (P(4)), however, the details of …

2009
Morbid obesity is associated with lower clinical pregnancy rates after in vitro fertilization in women with polycystic ovary syndrome.
Fertility and sterility ·doi:10.1016/j.fertnstert.2008.04.063

ObjectiveTo determine whether morbid obesity is associated with decreased pregnancy and live birth rates after IVF in women with polycystic ovary syndrome (PCOS).DesignRetrospective cohort study.SettingUniversity-based fertility center.Pati…

2005
Association between Beckwith-Wiedemann syndrome and assisted reproductive technology: a case series of 19 patients.
Fertility and sterility ·doi:10.1016/j.fertnstert.2004.07.964

ObjectiveAn association between assisted reproductive technique (ART) and specific imprinting mutations, such as Beckwith-Wiedemann syndrome (BWS), has recently been documented. Based on experiments in farm animals that demonstrated an asso…