Emond MJ

No ORCID on file · 3 papers in corpus · active 2008-2020
2020
Characterization of TP53 mutations in Pap test DNA of women with and without serous ovarian carcinoma.
Gynecologic Oncology ·doi:10.1016/j.ygyno.2019.11.124

ObjectivePap tests hold promise as a molecular diagnostic for serous ovarian cancer, but previous studies reported limited sensitivity. Furthermore, the presence of somatic mutations in normal tissue is increasingly recognized as a challeng…

2019
Ultra-Sensitive TP53 Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human Lifespan.
Cell reports ·doi:10.1016/j.celrep.2019.05.109

High-accuracy next-generation DNA sequencing promises a paradigm shift in early cancer detection by enabling the identification of mutant cancer molecules in minimally invasive body fluid samples. We demonstrate 80% sensitivity for ovarian …

2008
Genomic biomarkers to improve ulcerative colitis neoplasia surveillance.
The American Journal of Pathology ·doi:10.2353/ajpath.2008.080250

No adequate means exist to identify the minority of ulcerative colitis (UC) patients destined to undergo neoplastic progression. Recognition of this subset would advance UC cancer surveillance by focusing the available management options on…