Top journals
Frequent coauthors
- Risques RA 4
- Norquist BM 3
- Radke MR 3
- Katz R 2
- Hazard E 2
- Manhardt E 2
- Elizabeth M. Swisher 2
- Fredrickson J 2
- Kohrn BF 2
- Doll KM 1
2024
BackgroundIndividuals with germline BRCA1 and BRCA2 pathogenic variants (BRCA carriers) are at high risk of developing high grade serous ovarian carcinoma (HGSC). HGSC is predominantly driven by TP53 mutations, but mutations in this gene ar…
2022
BackgroundBreast cancer is a leading cause of death in premenopausal women. Progesterone drives expansion of luminal progenitor cells, leading to the development of poor-prognostic breast cancers. However, it is not known if antagonising pr…
2022
Current screening methods for ovarian cancer (OC) have failed to demonstrate a significant reduction in mortality. Uterine lavage combined with TP53 ultra-deep sequencing for the detection of disseminated OC cells has emerged as a promising…
2020
ObjectivePap tests hold promise as a molecular diagnostic for serous ovarian cancer, but previous studies reported limited sensitivity. Furthermore, the presence of somatic mutations in normal tissue is increasingly recognized as a challeng…