Wang X

Accurate patient-specific structural assessment of adenomyosis is essential for fertility-preserving treatment planning, but pelvic T2-weighted MRI is difficult to parse because the uterus, endometrium, ectopic glands, hemorrhagic foci, and…

BackgroundTraditional physiology teaching relies on 2D materials and static specimens, making it difficult to intuitively present complex anatomical structures and physiological mechanisms. 3D Intelligent Printing Technology (3DIPT) has dem…

RNA modification has been established as a pivotal field in epitranscriptomics, representing an emerging, dynamic, and precise regulatory layer in gene expression control. N6-methyladenosine (m6A), the most prevalent internal RNA modificati…

The age-related decline in oocyte quality constitutes a major cause of reduced female fertility. In this study, we investigated the potential of stromal cell-derived factor-1 (SDF-1) to counteract oocyte deterioration during reproductive ag…

BACKGROUND: Endometriosis has a substantial immune component, but the cellular contexts of genetically regulated disease susceptibility remain incompletely resolved. METHODS: We tested single-cell cis-eQTL instruments from 20 OneK1K periph…

Xin Wang, Guanglei Yao, Wei DingDepartment of Urology, The Second People’s Hospital of Wuhu, Wuhu, Anhui, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wei Ding, Department of Urology, The Second P…

Varicocele-induced decline in sperm quality is a common cause of male infertility. While varicocelectomy improves semen parameters, the mechanisms remain unclear. Recent studies suggested that small noncoding RNAs (sncRNAs) in sperm play a …

Females with iron overload suffer from follicular dysplasia, and effective therapeutic strategies for preserving fertility remain lacking. As a natural aliphatic polyamine, spermidine exerts antioxidant activity and plays an anti-ferroptosi…

BACKGROUND: Pyometra is an uncommon gynecologic disorder characterized by the accumulation of pus within the uterine cavity typically resulting from cervical obstruction. Spontaneous perforation of pyometra (SPP) is extremely rare but may r…

Oral delivery of protein and peptide therapeutics (PPs) offers a non-invasive, patient-friendly alternative to parenteral administration, yet faces multiple formidable barriers due to the complex gastrointestinal (GI) environment. This revi…

Plant metabolites used in traditional Chinese medicine (TCM) can form supramolecular assemblies in decoctions or in formulations prepared from purified molecules. These experimental settings support different conclusions. This narrative rev…

INTRODUCTION: Adenomyosis, which affects > 20% of reproductive-age women, is a major cause of infertility. Defective decidualization of endometrial stromal cells (ESCs) is a key pathogenic feature of adenomyosis; however, the underlying red…

BACKGROUND: Implantation failure is the most common cause of pregnancy failure and is a major limiting factor in assisted reproduction. Plasma microRNA (miRNA) expression profiles show dynamic changes among individuals with successful impla…

OBJECTIVE: This study aimed to investigate the variations in junctional zone (JZ) ultrasonographic parameters using three-dimensional transvaginal ultrasound (3D-TVS) across different age groups and evaluate their diagnostic potential for a…

Palmitoylethanolamide (PEA) is an endogenous fatty acid amide that has garnered significant attention due to its potential multiple antitumor mechanisms. This review first explores the current statuses and challenges faced in tumor preventi…

Fibrosis is a defining feature of endometriosis (EMS). Our previous single-cell RNA sequencing (scRNA-seq) revealed myofibroblasts (MFBs) as the predominant cells in ectopic endometrium (ECE), mainly derived from fibroblast-to-myofibroblast…

Globally, ovarian cancer remains a leading cause of gynecologic cancer death. This poor prognosis is primarily attributed to advanced disease at diagnosis, a high propensity for recurrence, and the inadequate therapeutic efficacy of current…

To mark 5 years of Cell Genomics, we asked authors across China to reflect on their research and the field of genomics. Together, these voices reflect on their findings, publishing, belonging to a community, and what shape the field's next …

This study aimed to investigate the pathogenic mechanisms of jaw cysts by screening for differentially expressed proteins in the tissues of patients with jaw cysts using proteomic techniques. Tissue samples were collected from 4 patients wi…

PURPOSE: Vaginal natural orifice transluminal endoscopic surgery (vNOTES) is an innovative minimally invasive procedure. The study aimed to evaluate whether vNOTES achieves non-inferior results compared to conventional laparoscopy in patien…

ObjectiveTo evaluate the accuracy of multimodal vaginal ultrasound in assessing post-caesarean scar healing.MethodsA systematic review and meta-analysis were conducted on Chinese and English studies using multimodal vaginal ultrasound to di…

OBJECTIVE: This study aimed to develop a predictive model for the risk of no usable blastocyst formation in patients with normal ovarian reserve undergoing IVF. METHODS: The model was derived from 7,901 patients who underwent their first o…

Mengmeng Sun,1,2,* Xinyi Deng,3,* Hui Xing,1,4 Rui Zhang,3 Bingbing Fu,1 Tao Ai,5 Fang Wang,6 Xuechun Wang,6 Lei Chen,6 Xiaogang Mao,1,4 Feng Wu3 1Department of Obstetrics and Gynecology, Xiangyang Central Hospital, Affiliated Hospi…