Fu X

ORCID: 0009-0009-2625-5662 · 69 papers in corpus
other 2021
Trials ·doi:10.1186/s13063-021-05834-0

BACKGROUND: Primary dysmenorrhea (PD) is one of the main gynecological complaints in women of child-bearing age, but limited effective treatments are available. Guizhi Fuling Wan (GFW), one of the most widely known traditional Chinese medic…

other 2021
Frontiers in cellular and infection microbiology ·doi:10.3389/fcimb.2021.788836

The diagnosis of endometriosis is typically delayed by years for the unexclusive symptom and the traumatic diagnostic method. Several studies have demonstrated that gut microbiota and cervical mucus potentially can be used as auxiliary diag…

other 2021
Experimental and therapeutic medicine ·doi:10.3892/etm.2021.10675

Endometriosis (EM), a benign aseptic inflammatory disease, is associated with the presence of endometrial foci. Pain, one of its typical symptoms, has been reported as a constant stressor, but the etiology and pathogenesis of EM-associated …

lab-animal 2021
Cell death discovery ·doi:10.1038/s41420-021-00751-2

Endometriosis is one of the most common disorders that causes infertility in women. Iron is overloaded in endometriosis peritoneal fluid (PF), with harmful effects on early embryo development. However, the mechanism by which endometriosis p…

observational 2021
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-021-00738-9

BACKGROUND: Thin endometrial thickness (EMT) has been suggested to be associated with reduced incidence of pregnancy rate after in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) treatment, but the effect of thin endometrium…

lab-animal 2021
PeerJ ·doi:10.7717/peerj.11087

BACKGROUND: Guizhi Fuling Wan (GZFLW) is a widely used classical Chinese herbal formulae prescribed for the treatment of endometriosis (EMs). This study aimed to predict the key targets and mechanisms of GZFLW in the treatment of EMs by net…

review 2020
Frontiers in physiology ·doi:10.3389/fphys.2020.614591

Acute pancreatitis is a potentially severe inflammatory disease that may be associated with a substantial morbidity and mortality. Currently there is no specific treatment for the disease, which indicates an ongoing demand for research into…

lab-animal 2020
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-020-00301-8

Endometriosis is generally characterized as a tumor-like disease because of its potential for distant metastasis and local tissue invasion, while whether osteopontin (OPN) plays a role in the pathogenesis of endometriosis has not been thoro…

other 2019
Systems biology in reproductive medicine ·doi:10.1080/19396368.2019.1688425

The objective of this study was to identify proteins that are differentially expressed in the cystic wall tissues of ovarian endometriotic cysts, simple ovarian cysts, and in normal ovarian tissues. Specimens of ovarian endometriotic cyst w…

lab-animal 2018
Toxicology letters ·doi:10.1016/j.toxlet.2018.03.009

Polychlorinated biphenyls (PCBs), as part of environmental contaminants, have been proved to be related to endometriosis. This study is to investigate the effect of PCB 104 on cell migration, invasion and resultant gene expression in endome…

case-report 2017
International journal of surgical pathology ·doi:10.1177/1066896917727595

Appendiceal or cecal endometriosis with intestinal metaplasia is uncommon and may mimic mucinous tumors of the appendix. A 50-year-old woman was found incidentally to have an ileocecal lesion. In the intraoperative histological examination,…

lab-animal 2017
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie ·doi:10.1016/j.biopha.2017.07.089

In the present study, we examined the effects of rhein on pituitary gland implantation-induced adenomyosis, an animal model which mimics human adenomyosis. Oral administration of rhein dose-dependently attenuated hyperplastic and hypertroph…

observational 2017
Medical science monitor : international medical journal of experimental and clinical research ·doi:10.12659/msm.905226

BACKGROUND Studies have shown that the concentration of interleukin (IL)-6 in peritoneal fluid is increased in patients with endometriosis; however, whether the disorders involving IL-6 contribute to the development of endometriosis is stil…

lab-animal 2017
International journal of clinical and experimental pathology

This study aimed to investigate the potential role of microRNA-202-5p (miR-202-5p) in regulating myocardial ischemia-caused injury and to explore the underlying mechanisms. Rat embryonic ventricular cardiomyocyte-derived H9c2 cells were tre…

lab-animal 2016
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.1612835113

Forkhead box protein A1 (FOXA1) is a pioneer factor of estrogen receptor α (ER)-chromatin binding and function, yet its aberration in endocrine-resistant (Endo-R) breast cancer is unknown. Here, we report preclinical evidence for a role of …

other 2015
Journal of Minimally Invasive Gynecology ·doi:10.1016/j.jmig.2015.08.646
meta-analysis 2014
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2014.04.039

OBJECTIVE: Catechol-O-methyltransferase (COMT) 158G/A and cytochrome P450-1B1 (CYP1B1) 432C/G gene polymorphisms have been associated with the risk of endometriosis and adenomyosis, but results remain inconclusive. The aim of this study was…

other 2014
Human molecular genetics ·doi:10.1093/hmg/ddu330

Endometriosis is a complex and enigmatic disease that arises from the interplay among multiple genetic and environmental factors. The defining feature of endometriosis is the deposition and growth of endometrial tissues at sites outside of …

observational 2013
International journal of fertility & sterility

BACKGROUND: The present study aims to explore the significance of the expression of growth hormone-releasing hormone (GHRH) and its receptor splice variant 1 (GHRHSV1) in endometriosis (EM). MATERIALS AND METHODS: In this research paper 80…