Andrew V. Schally

ORCID: 0000-0003-1273-6747 · 14 papers in corpus · active 1977-2017

Study types

  • article 6
  • other 4
  • book-chapter 2
  • review 2

Condition tags

  • endometriosis 10
  • dysmenorrhea 2
  • dyspareunia 2
  • infertility 1
other 2017
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719117691140

Endometriosis is a benign gynecologic disorder causing dysmenorrhea, pelvic pain, and subfertility. Receptors for the growth hormone-releasing hormone (GHRH) were found in endometriotic tissues. Antagonists of GHRH have been used to inhibit…

article 2015
·doi:10.5301/je.5000208

Agonists of luteinizing hormone-releasing hormone (LHRH) induce a reversible hypoestrogenic state through the down-regulation of LHRH receptors and desensitization of the pituitary. Since endometrial implants are estrogen sensitive, LHRH ag…

book-chapter 2010
·doi:10.5005/jp/books/11032_25
other 2009
Neuropeptides ·doi:10.1016/j.npep.2009.03.001

The decapeptide Cetrorelix, an LHRH antagonist, inhibits gonadotropin and sex steroid secretion. Cetrorelix is used for IVF-ET procedures and for the treatment of patients with prostate carcinoma, benign prostatic hyperplasia, endometriosis…

other 2009
Fertility and sterility ·doi:10.1016/j.fertnstert.2008.04.048

OBJECTIVE: To determine possible involvement of splice variant 1 (SV1), a variant of the pituitary growth hormone-releasing hormone (GHRH) receptor, in the development of endometriosis. DESIGN: Comparative and laboratory study. SETTING: U…

review 2007
Nature clinical practice. Endocrinology & metabolism ·doi:10.1038/ncpendmet0399

This article reviews the clinical uses of agonists and antagonists of luteinizing-hormone-releasing hormone (LHRH), also known as gonadotropin-releasing hormone. In particular, the state of the art treatment of breast, ovarian and prostate …

other 2004
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.0400605101

Our previous studies showed that treatment of female rats with large doses of Cetrorelix, an antagonist of luteinizing hormone-releasing hormone (LHRH), reduces levels of serum LH, estradiol, progesterone, and the concentration of pituitary…

review 1999
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.3109/09513599909167587

In the 28 years that have passed since the elucidation of the structure of luteinizing hormone-releasing hormone (LH-RH), diverse clinical applications in the field of reproductive medicine and related fields have been established for agoni…

book-chapter 1993
·doi:10.1007/978-94-011-1470-7_337
article 1989
International journal of fertility

Eight menstrually cycling women with proven endometriosis were treated with a delayed-release preparation of the superactive agonist D-Trp-6-LH-RH in biodegradable microcapsules, administered intramuscularly at intervals of 16 to 36 days fo…

article 1987
International journal of fertility

Reversible temporary medical oophorectomy using long-acting agonist analogs of LH-RH was tried in three infertile patients suffering from large endometriomas of the ovary. These patients had stage IV disease according to the revised 1985 cl…

article 1978
·doi:10.1016/0010-7824(78)90061-6
article 1978
·doi:10.1016/0010-7824(78)90019-7
article 1977