Signe Altmäe

No ORCID on file · 38 papers in corpus · active 2007-2026

Study types

  • article 15
  • other 6
  • review 3
  • book-chapter 2
  • letter 1

Condition tags

  • endometriosis 22
  • infertility 15
  • irritable_bowel_syndrome 1
  • adenomyosis 1
2017
Scientific reports ·doi:10.1038/s41598-017-10098-3

Previous transcriptome studies of the human endometrium have revealed hundreds of simultaneously up- and down-regulated genes that are involved in endometrial receptivity. However, the overlap between the studies is relatively small, and we…

book-chapter 2017
·doi:10.1007/978-3-319-59856-7_12
article 2016
Fertility and sterility ·doi:10.1016/j.fertnstert.2016.05.023

ObjectiveTo determine expression of stanniocalcin-1 (STC1) in human endometrium with and without endometriosis and its regulation by steroid hormones.DesignLaboratory study.SettingUniversity.Patient(s)Nineteen women with endometriosis and 3…

2015
Human reproduction (Oxford, England) ·doi:10.1093/humrep/deu296

Study questionAre mutations in NLRP2/7 (NACHT, LRR and PYD domains-containing protein 2/7) or KHDC3L (KH Domain Containing 3 Like) associated with recurrent pregnancy loss (RPL) or infertility?Summary answerWe found no evidence for mutation…

article 2015
·doi:10.1016/j.fertnstert.2014.12.085
letter 2015
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2015.09.008
2014
Human reproduction update ·doi:10.1093/humupd/dmt048

Background'Omics' high-throughput analyses, including genomics, epigenomics, transcriptomics, proteomics and metabolomics, are widely applied in human endometrial studies. Analysis of endometrial transcriptome patterns in physiological and …

2013
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719112453507

MicroRNAs (miRNAs) act as important epigenetic posttranscriptional regulators of gene expression. We aimed to gain more understanding of the complex gene expression regulation of endometrial receptivity by analyzing miRNA signatures of fert…

article 2011
·doi:10.1093/humrep/26.s1.80
article 2010
·doi:10.1177/1933719110388849

We set up to analyze polymorphisms in hyaluronan-binding protein 2 (HABP2) gene in healthy fertile women (n = 158) and in women with unexplained infertility (n = 116) and to investigate the potential role of HABP2 in receptive endometrium. …

article 2009
Reproductive biomedicine online ·doi:10.1016/s1472-6483(10)60009-0

Progress has been made towards ascertaining the genetic predictors of ovarian stimulation in IVF. Aromatase cytochrome P450, encoded by the CYP19A1 gene, catalyses a key step in ovarian oestrogen biosynthesis. Hence, the aromatase gene is a…

article 2008
·doi:10.1016/j.fertnstert.2008.04.010

ObjectiveTo study the expression of leukemia inhibitory factor (LIF), its receptors LIFR and gp130, and its inhibitor SOCS1 in endometria from fertile women and infertile women with unexplained infertility. Signaling through the LIF pathway…

other 2007
Molecular human reproduction ·doi:10.1093/molehr/gam035

The outcome of in vitro fertilization (IVF) depends substantially on the effectiveness of controlled ovarian hyperstimulation (COH) induced by administration of follicle-stimulating hormone (FSH). In COH, endogenously produced estrogens ext…