PURPOSE: The present study aims to investigate the number of surgical procedures performed by Italian residents and their confidence to carry out different surgeries in obstetrics and gynecology. METHODS: The present study is a national su…
Many authors have reported an epidemiologic relationship between endometrial polyps and endometriosis. The joining link could be an unopposed and unbalanced estrogenic milieu. The prevalence of both, endometrial polyps and endometriosis, is…
INTRODUCTION: Deep infiltrating endometriosis (DIE) affects between 3.8% and 37% of all endometriosis patients, mostly affecting rectovaginal septum or retrocervical space and characterized by the severe endometriosis-related complaints. No…
PURPOSES: The primary objective is to assess the long-term quality of life (QoL) and gastrointestinal well-being in patients with endometriosis (DIE) who underwent segmental resection (SR), through specific questionnaires focused on endomet…
STUDY OBJECTIVE: Beside the pain, there are 2 further problems in the management of endometriosis: the high recurrence rate (10% per year) and the high rate of impaired fertility. The objective of this study was to investigate the pathogene…
PURPOSE: Superficial peritoneal endometriotic (pEM) lesions are composed of endometrial glands and stroma, in addition to a third component-myofibroblasts and smooth muscles (SM)-like cells. The latter develops secondary to a metaplasia. In…
STUDY OBJECTIVE: To evaluate the clinical presentation and surgical outcome in patients with deep lateral pelvic endometriosis (dLPE). DESIGN: A retrospective multicentric study (Canadian Task Force classification II-2). SETTING: Universi…
In this study, we report about a patient with extra-uterine endometriosis (EM) in the abdominal wall muscle with evident metaplasia based on the abundant alpha smooth muscle actin (ASMA)-expressing myofibroblasts. Laparotomy excision of the…
BACKGROUND: The published data about alcohol consumption and uterine myoma are scanty and controversial: some studies found positive association whereas other studies showed no association. OBJECTIVES: To conduct a systematic review and me…
Introduction Endometriosis is associated with both cyclic and non-cyclic pelvic pain. Many patients do not remain symptom free, even after guideline-oriented treatment. This study aimed to identify differences in endometriosis-associated pa…
Pain is the most important symptom in patients with endometriosis, and its management is truly challenging. Due to the different localization of the endometriotic lesions in the pelvis, patients suffer from visceral and somatic pain or both…
BACKGROUND: Adenomyosis (AM) uteri exhibit hyperperistalsis. The latter causes a chronic tissue trauma at the endometrial-myometrial junctional zone (EMJZ). Upon tissue trauma, microdehiscences in the myometrium facilitate the translocation…
To identify factors influencing the differential pain pathogenesis in peritoneal endometriosis (pEM) and peritoneal carcinomatosis in ovarian cancer (pOC), we undertook an experimental study. Tissue samples of 18 patients with pEM, 15 patie…
Establishing the diagnostic and surgical management of the inguinal Endometriosis, with further investigation of the biological character.The imaging findings of CT and PET-CT, biopsy, ultrasound, open surgery of the inguinal region with in…
OBJECTIVE: To identify and characterize endometriosis-associated immune cell infiltrates (EMaICI). Furthermore, to define occurrence and size of EMaICI in various types of endometriosis. METHODS: Immune cells were characterized in samples …
STUDY OBJECTIVE: To evaluate the feasibility of a novel laparoscopic procedure for complete eradication of diaphragmatic endometriosis (DE). DESIGN: A retrospective multicenter study (Canadian Task Force Classification II-2). SETTING: Uni…
STUDY HYPOTHESIS: Loss of protein BAF250a (ARID1A) expression is present in women with rectovaginal deep-infiltrating endometriosis (DIE) and endometriosis affecting the pelvic sentinel lymph nodes (PSLN). STUDY FINDING: Partial loss of pr…
Endometriosis is a chronic inflammatory disease and one of the most common causes of pelvic pain. The mechanisms underlying pain emergence or chronic inflammation during endometriosis remain unknown. Several chronic inflammatory diseases in…
Immer wieder tritt bei Frauen nach laparoskopisch assistierter supracervikaler Hysterektomie (LASH) eine rektovaginale Endometriose auf, die operativ behandelt werden muss. Das Anliegen dieser Studie war es Patientinnen mit rektovaginaler E…
Endometriose ist eine Östrogenabhängige inflammatorische Erkrankung und eine der häufigsten Ursachen für Unterbauchschmerzen. Die genaue Pathogenese der Erkrankung sowie die Ursachen der Schmerzentstehung sind bislang noch ungeklärt. Neuere…
Endometriose, die zweithäufigste benigne gynäkologische Erkrankung, ist assoziiert mit chronischen Unterbauchschmerzen, Dysmenorrhoe, Dyspareunie und Dyschezie. Trotz der meist im Vordergrund stehenden Schmerzsymptomatik sind die Schmerzmec…
Die peritoneale Endometriose (pEM) und die Peritonealkarzinose des Ovarialkarzinoms (pOC) sind als Pathologien des Peritoneums mit sekundärer Absiedlung von gynäkologischer Bedeutung.
Endometriosis is a prevalent benign disease, despite sharing several similarities with malignancies, such as the possibility of lymphatic spread. In malignancies, chemokines play a sovereign role in the process of metastasis. Metastasis-rel…
Adenomyose uteri (AM) wird durch das Vorkommen von ektopen endometrialen Drüsen und Stromazellen im Myometrium charakterisiert. Als aktuelles Pathogenese Konzept der AM wird die „Tissue Injury And Repair (TIAR)“ Theorie diskutiert. Sie besa…