Lei Cheng

No ORCID on file · 7 papers in corpus · active 2003-2024

Study types

  • article 6
  • other 1

Condition tags

  • adenomyosis 4
  • dysmenorrhea 2
  • endometriosis 2
other 2024
Extracellular vesicle-encapsulated miR-25-3p promotes epithelial-mesenchymal transition and migration of endometrial epithelial cells by inducing macrophage polarization
Molecular human reproduction ·doi:10.1093/molehr/gaae010

The pathogenesis of adenomyosis is closely related to the epithelial-mesenchymal transition and macrophages. MicroRNAs have been extensively investigated in relation to the epithelial-mesenchymal transition in a range of malignancies. Howev…

article 2023
6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio) Hexanol Inhibits Proliferation and Induces Apoptosis of Endometriosis by Regulating Glutathione S-Transferase Mu Class 4
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-023-01207-x
article 2023
Extracellular vesicles contribute to EMT in adenomyosis by inducing macrophage polarization
Biology of reproduction ·doi:10.1093/biolre/ioad015

Adenomyosis is a benign disease, but it exhibits a metastatic property similar to tumors. Its pathogenesis is still unclear. One theory is that adenomyosis is the result of epithelial-mesenchymal transition (EMT) in displaced embryonic Mull…

article 2021
A clinical observational study on the efficacy of subcutaneous etonogestrel implants for adenomyosis in 20 patients
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.1080/09513590.2021.1922886

Objective: To evaluate the efficacy of subcutaneous etonogestrel implants for adenomyosis.Methods: We conducted a clinical observational study of 20 patients suffering from adenomyosis treated with subcutaneous etonogestrel implants from Au…

article 2021
Subcutaneous etonogestrel implant combined with endometrial ablation for the treatment of adenomyosis: two case reports
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.15084

Adenomyosis is a common disease that affects many premenopausal women. Two patients with adenomyosis, aged 51 and 42 years, presented with dysmenorrhea and increased menstrual volume. They refused laparoscopy or laparotomy surgery and were …

article 2019
Lipoxin A4 Suppresses IL-1β-Induced Cyclooxygenase-2 Expression Through Inhibition of p38 MAPk Activation in Endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719119828115
article 2003
Effect of long-term treatment with low-dose mifepristone on the endometrium
·doi:10.1093/humrep/deg022

BACKGROUND: Mifepristone in low daily doses has contraceptive potential by inhibiting ovulation and menstruation. Because follicular development is maintained, the endometrium is exposed to estrogen for prolonged periods unopposed by proges…