Viviane Cavalcanti

Aberrant FOXP3 gene expression in eutopic and ectopic endometrium of infertile women with endometriosis orIgInal

Background: Immunological theories suggest that changes in the immune system could prevent the ability to eliminate the endometrium of the pelvic cavity. In women with endometriosis is possible that changes in immunity mediated by T cells f…

ObjectiveTo evaluate the frequency of polymorphism G-765C (rs20417) of the COX-2 gene and the expression of this gene in the endometrium of women with endometriosis.Study designThis is a case-control study of 365 women with endometriosis (2…

Background and aimsConsidering the complex cellular and molecular mechanisms involved in endometriosis formation and progression and the similarities concerning the association of endometriosis with tumorigenesis and metastasis, we hypothes…

BACKGROUND: Endometriosis is a chronic condition whose pathophysiology is unknown, but there is evidence suggesting a link with oxidative stress. Paraoxonase is a serum enzyme which circulates associated with high-density lipoprotein (HDL).…

We aimed to evaluate the frequency of the G-765C/rs20417 polymorphism in theCOX2gene and the gene expression in the endometrium of women with endometriosis. We performed a casecontrol study comprising 257 infertile and30 fertile women diagn…

IntroductionAn aberrant immunologic mechanism has been suggested to be involved in the pathogenesis of endometriosis. Nuclear factor-kB (NF-kB) plays a key role in the immune and inflammatory response and modulates cell proliferation, apopt…

IntroductionTyrosine kinase 2 gene (TYK2) is part of the janus kinase (JAK) that binds to the type I interferon-α receptor (IFNAR) on the cell surface of IFN-producing cells, and have crucial importance in the etiology of autoimmune and inf…