Strug MR

No ORCID on file · 6 papers in corpus · active 2014-2022

Study types

  • article 1

Condition tags

  • endometriosis 1
  • infertility 1
2022
Ultrasonographic technique to differentiate enhanced myometrial vascularity/arteriovenous malformation from retained products of conception.
Journal of ultrasound ·doi:10.1007/s40477-021-00574-y

PurposeTo objective of this study is to discuss the ultrasonographic technique to diagnose uterine enhanced myometrial vascularity/arteriovenous malformation (EMV/AVM) and differentiate it from retained products of conception. The study als…

2019
The Notch Family Transcription Factor, RBPJκ, Modulates Glucose Transporter and Ovarian Steroid Hormone Receptor Expression During Decidualization.
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719118799209

During decidualization, endometrial stromal cells differentiate into a secretory phenotype to modulate the uterine microenvironment and promote embryo implantation. This highly metabolic process relies on ovarian steroid receptors and gluco…

2018
RBPJ mediates uterine repair in the mouse and is reduced in women with recurrent pregnancy loss.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology ·doi:10.1096/fj.201701032r

Unexplained recurrent pregnancy loss (uRPL) is associated with repeated embryo loss and endometrial repair with elevated endometrial expression of inflammatory cytokines, including IFN-γ. Notch signaling through its transcription factor rec…

2016
Aberrant activation of canonical Notch1 signaling in the mouse uterus decreases progesterone receptor by hypermethylation and leads to infertility.
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.1520441113

In mammalian reproduction, implantation is one of the most critical events. Failure of implantation and the subsequent decidualization contribute to more than 75% of pregnancy losses in women. Our laboratory has previously reported that inh…

2016
Intrauterine human chorionic gonadotropin infusion in oocyte donors promotes endometrial synchrony and induction of early decidual markers for stromal survival: a randomized clinical trial.
Human reproduction (Oxford, England) ·doi:10.1093/humrep/dew080

Study questionDoes a single intrauterine infusion of human chorionic gonadotropin (hCG) at the time corresponding to a Day 3 embryo transfer in oocyte donors induce favorable molecular changes in the endometrium for embryo implantation?Summ…

article 2014
Decreased Notch Pathway Signaling in the Endometrium of Women With Endometriosis Impairs Decidualization
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2014-3720

CONTEXT: Endometriosis is a common gynecological disease affecting one in 10 women of reproductive age and is a major cause of pelvic pain and impaired fertility. Endometrial stromal cells of women with endometriosis exhibit a reduced respo…