Massimo Candiani

No ORCID on file · 172 papers in corpus · active 1991-2026

Study types

  • article 104
  • review 31
  • other 19
  • letter 4
  • meta-analysis 3

Condition tags

  • endometriosis 144
  • infertility 25
  • endometrioma 25
  • chronic_pelvic_pain 12
  • dysmenorrhea 9
  • adenomyosis 8
  • dyspareunia 7
  • bowel_endometriosis 5
  • die_deep_infiltrating 5
  • bladder_endometriosis 3
article 2015
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719115578930

Endometriosis is caused by the displacement of endometrium outside the uterus contributing heavily to infertility and debilitating pelvic pain. Ectopic adhesion and growth are believed to occur under the influence of a favorable hormonal en…

article 2014
Annals of the New York Academy of Sciences ·doi:10.1111/nyas.12411

Endometriosis is an estrogen-dependent inflammatory disease defined by the growth of endometrial stroma and glands outside of the uterus. Epidemiological and clinical studies show that estrogen is essential for the growth of endometriosis. …

article 2014
other 2014
Gynecologic oncology ·doi:10.1016/j.ygyno.2014.03.017

OBJECTIVE: Endometrioid and clear cell ovarian tumors have been referred to as "endometriosis associated ovarian cancers". However, very few studies have compared clinical and prognostic features of endometriosis-associated cancers or cance…

article 2014
·doi:10.1016/j.jmig.2014.08.066
review 2014
Expert opinion on pharmacotherapy ·doi:10.1517/14656566.2014.943734

INTRODUCTION: Dienogest (DNG) is an oral progestin, derivative of 19-nortestosterone, that has recently been introduced for the treatment of endometriosis. AREAS COVERED: This review examines the clinical efficacy, safety and tolerability o…

review 2014
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.12310

Malignant degeneration of endometriosis in the inguinal region is rare, and has only been reported in six cases in the literature, none of which was detected during pregnancy. We present the first case of endometriosis-associated adenocarci…

article 2014
article 2014
Human Reproduction ·doi:10.1093/humrep/det466

STUDY QUESTION: Does the iron content of an endometrioma represent a potential source of toxicity for the adjacent follicles? SUMMARY ANSWER: The presence of an endometrioma increases iron and H/L ferritin levels, and transferrin receptor (…

article 2014
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2014.10.031

ObjectiveCohort and case-control studies have suggested that adult physical activity (PA) may lower endometriosis risk and improve symptoms, but evidence is still controversial. To add information on leisure and occupational PA impact, if a…

article 2014
2014
BioMed research international ·doi:10.1155/2014/903848

Pelvic pain is a common condition which significantly deteriorates health-related quality of life. The most commonly identified causes of pain in the pelvic region are gynaecologic, urologic, gastrointestinal, neurological, and musculoskele…

review 2014
Human reproduction update ·doi:10.1093/humupd/dmt053

BACKGROUND: Clinical data suggest that the presence of an ovarian endometrioma may cause per se damage to the surrounding otherwise healthy ovarian tissue. However, the basic research has so far done a limited job in trying to understand th…

review 2014
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719114529374

Ovarian endometriomas are found in a consistent proportion of patients with endometriosis and are associated with a more severe form of the disease. The endometriotic tissue lining the inside of the endometrioma has been extensively studied…

article 2014
Fertility and sterility ·doi:10.1016/j.fertnstert.2014.02.040

ObjectiveTo analyze the WNT/β-catenin signaling pathway in luteinized granulosa cells from women with and without endometriosis in relation to cellular apoptosis.DesignBasic.SettingUniversity hospital.Patient(s)Patients with a laparoscopic …

review 2014
Expert opinion on pharmacotherapy ·doi:10.1517/14656566.2014.916279

INTRODUCTION: Over the past 30 years, gonadotropin-releasing hormone agonists (GnRH-a) have been used to induce a hypoestrogenic status in women with endometriosis with the aim to cause an improvement in pain symptoms similar to that observ…

2014
Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-12-47

Accumulating evidence from animal and human studies suggests that vitamin D is involved in many functions of the human reproductive system in both genders, but no comprehensive analysis of the potential relationship between vitamin D status…

review 2013
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2012.12.011

A connection between dietary factors and endometriosis onset has become a topic of interest mostly due to the observation that physiological and pathological processes of the disease can be influenced by diet. This paper systematically revi…

article 2013
·doi:10.5301/je.5000156

Controversy exists regarding the pathogenesis of endometriotic ovarian cysts. Different and complex theories have been proposed over the years since the description of chocolate cysts by Sampson in 1921. We have herein reviewed findings in …

review 2012
Journal of medical genetics ·doi:10.1136/jmedgenet-2012-101257

BACKGROUND: Although endometriosis may benefit from primary prevention measures, the epidemiological risk factors identified are equivocal. Two genome-wide association studies (GWAS) have been conducted for endometriosis in two different et…

letter 2012
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2012.05.016
article 2012
Acta obstetricia et gynecologica Scandinavica ·doi:10.1111/j.1600-0412.2012.01366.x

OBJECTIVE: Limited attention has been focused on the medical treatment of bowel endometriosis. This study evaluates the efficacy of administration of a continuous low-dose oral contraceptive in treating pain and other symptoms associated wi…

review 2012
Human reproduction update ·doi:10.1093/humupd/dms001

BACKGROUND: Endometriosis has been associated with specific morphometric characteristics and pigmentary traits. The purpose of this study was to systematically review prior publications dealing with this aspect in order to revisit phenotypi…

article 2012
·doi:10.1007/s13669-012-0013-8
review 2012
Molecular human reproduction ·doi:10.1093/molehr/gas037

The endocannabinoid system consists of an array of endogenously produced bioactive lipids that activate cannabinoid 1 (CB1) and 2 (CB2) receptors. Alterations of this system have been described in almost every category of disease. These cha…