Juan A Garcia-Velasco

Research rarely progresses in a straight line. It is more like an unpredictable front, marked by bursts of brilliance that fade after a few years, sudden breakthroughs, periods of stagnation, rediscoveries of forgotten ideas and occasional …

STUDY QUESTION: What are the clinical pregnancy and live birth rates in women who underwent up to two more euploid blastocyst transfers after three failures in the absence of another known factor that affects implantation? SUMMARY ANSWER: …

Although a wealth of data has been published regarding fertility preservation (FP) in women with malignant diseases who receive gonadotoxic treatment, the role of FP in non-malignant conditions has been studied to a much lesser extent. Thes…

BACKGROUND: Endometriosis is known to have an impact on fertility and it is common for women affected by endometriosis to require fertility treatments, including in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI), to im…

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table of contents † Endometriomas and ovarian responsiveness † Endometrioma-related impact on ovarian responsiveness: a primary or a secondary event? † Treatment prior to IVF † The risks of surgery or expectant management

OBJECTIVE: To evaluate IVF outcome in women with unoperated bilateral endometriomas. DESIGN: Multicenter retrospective cohort study. SETTINGS: Two infertility units. PATIENT(S): Thirty-nine women with bilateral endometriomas matched with…

Outcomes of in vitro fertilization cycles in women with endometriosis are significantly worse than in patients without this condition. The impact of endometriosis on ovarian reserve and the quality of retrieved oocytes seems evident. Lower …

PURPOSE OF REVIEW: To summarize the literature related to the value of surgery in endometrioma-associated infertility and present the most recent evidence in support or against the surgical removal of endometriomas with special attention be…

background: There is a growing consensus that ovarian endometriomas should not be systematically removed in women selected for IVF. However, some recent evidence suggested that the presence of these cysts may negatively affect the course of…

The use of aromatase inhibitors (AIs) in IVF patients remains controversial. AIs can be considered for ovulation induction for IVF in women who are normal and poor responders, are at risk of ovarian hyperstimulation syndrome or thrombosis, …

Previous studies in an experimental mouse model of endometriosis have shown that the dopamine agonist (DA) cabergoline (Cb2) reduces angiogenesis and endometriotic lesions, hypothetically binding to the dopamine receptor type-2 (DRD2). To d…

The classic, unproven dogma that ovarian endometrioma should be removed in all infertile women prior to IVF has been recently questioned. There is currently insufficient data to clarify whether the endometrioma-related damage to ovarian res…

Apoptosis is a physiologic process that deletes unwanted cells without inducing an inflammatory reaction. Survival of endometriotic implants is associated with decreased apoptosis and an inflammatory environment. The most widely accepted th…