Qiong Zhang

Autophagy has emerged as an important process of cell metabolism. With continuous in-depth research on autophagy, TFEB has been a key transcription factor regulating autophagy levels in recent years. Studies have established that TFEB regul…

Platelets are reprogrammed by cancer via a process called education, which favors cancer development. The transcriptional profile of tumor-educated platelets (TEPs) is skewed and therefore practicable for cancer detection. This intercontine…

OBJECTIVE: To investigate the roles of the cGAS-STING signal pathway and autophagy in the disease progression of endometriosis and to explore the regulatory mechanism of the cGAS-STING signal pathway on autophagy. DESIGN: A case-control ex…

BACKGROUND: Endometriosis (EMs) is a benign, but potential metastatic, gynecological disease. Our current study aims to examine whether all-trans retinoic acid (ATRA) inhibits the epithelial-to-mesenchymal transition (EMT) of endometriotic …

Abstract Objective To develop a model that uses hematological indexes and clinical characteristics to help estimate the probability of endometriosis in patients with ovarian cysts. Methods A retrospective study was conducted on 2242 patient…

Double-stranded DNA (dsDNA) sensor cyclic-GMP-AMP synthetase (cGAS) and its downstream interferon gene stimulator (STING) act as important immune monitoring media have become a research hotspot. cGAS-STING pathway may play a key role in the…

Endometriosis is a benign gynecologic disease, but it is similar in behavior to malignant tumors, so it is called “benign gynecologic cancer”. At present, its pathogenesis is not fully understand. Autophagy has been the focus of recent rese…

Uterine peristalsis plays a vital role in fertility and female reproductive health. Although uterine peristalsis is thought to be correlated with some hormones and uterine pathologies, the physiological mechanisms underlying uterine perista…

Objective: To explore a novel approach for the isolation of human endometriotic stem cells for further study in the stem cell theory of endometriosis. Materials and Methods: A serum-free medium (SFM) was used to isolate the stem cells from …

Objective: Our aim was to study the association between early-life factors and the development of endometriosis.Methods: This case–control study included 440 women with surgically confirmed endometriosis (cases) and 880 women without endome…

Endometriosis, a common gynecological disease, is associated with pelvic pain and infertility. Endometriosis affects approximately 10% of women, but that number increases to 30-50% in symptomatic premenopausal women. Despite the prevalence …

Objective: To establish the messenger RNA (mRNA) and long non-coding RNA (lncRNA) expression profiles in ectopic and eutopic endometrium and provide novel insights into endometriosis. Methods: The mRNA and lncRNA expression profiles were te…

Evaluation of cytotoxicity and transfection efficiency. (DOCX 14 kb)

Evaluation of cytotoxicity and transfection efficiency. (DOCX 14 kb)

BACKGROUND: Endometriosis is a common, benign, and estrogen-dependent disease characterized by pelvic pain and infertility. To date, the pathogenesis of endometriosis remains unclear. Recent studies have demonstrated that noncoding RNAs, in…

BACKGROUND: To study the effect of endometrial thickness and pattern measured using ultrasound upon pregnancy outcomes in patients undergoing IVF-ET. METHOD: One thousand nine hundred thirty-three women undergoing IVF treatment participated…