Li Z

Endometriosis (EMs) is a common disease in women of childbearing age, categorized into ovarian, superficial, and deep infiltrating endometriosis (DIE). Bladder endometriosis (BE) is a type of DIE with an incidence of approximately 1% among …

Wen Zhao,1 Zeting Li,2 Jianping Ou1 1Center for Reproductive Medicine, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, People’s Republic of China; 2Department of Endocrinology, The Seventh Affiliated Hospital, S…

OBJECTIVES: The aim of this study was to assess the clinical outcomes of ultrasound (US)-guided high-intensity focused ultrasound (HIFU) in patients with breast fibroadenoma (FA) of different sizes. MATERIALS AND METHODS: A total of 88 pat…

Extra-pelvic endometriosis always presents complex diagnostic challenges due to its non-specific symptoms. We describe a rare case of coexisting iatrogenic abdominal wall endometriosis (AWE) and thoracic endometriosis (TE) in a 33-year-old …

BACKGROUND: Myofascial pelvic pain syndrome (MPPS) is a common but often underdiagnosed cause of chronic pelvic pain in women, significantly affecting quality of life. Early and accurate identification of patients at risk is essential for i…

This study aimed to explore the causal link between immunophenotypes and adenomyosis using Mendelian randomization (MR). We conducted a bidirectional MR analysis on 731 immunophenotypes, employing inverse-variance weighted (IVW) as the prim…

BACKGROUND: Hyperuricemia (HUA) impairs sperm function via oxidative stress and metabolic dysregulation. This retrospective cohort study aimed to investigate the therapeutic effect of density gradient centrifugation (DGC) on HUA-associated …

Uterine fibroids are common among women of reproductive age and often recur after treatment. Accurate recurrence prediction is essential for guiding clinical decisions, yet existing models remain inadequate. This study aimed to develop a no…

OBJECTIVES: This study aimed to evaluate a clinical utility of preimplantation genetic testing for aneuploidy (PGT-A) in patients with recurrent pregnancy loss (RPL) and explore a population that benefits from it. METHODS: We analyzed 818 …

BACKGROUND: More than 500 patients have received cryopreserved ovarian tissue transplantation (OTT) worldwide, resulting in over 200 live births. Although guidelines recognize OTT as an effective fertility preservation method, there is no c…

Phthalate metabolites Mono- (2-ethylhexyl) phthalate(MEHP) and Phthalic Acid Monobenzyl Ester (MBZP) are widely present in the environment, can interfere with the endocrine system and accumulate in human tissues, and are closely related to …

Endometriosis (EMs) is a chronic gynecologic condition characterized by the growth of endometrial stromal and glandular tissue outside the uterine cavity of unknown etiology. Currently, ferroptosis resistance, increased glycolysis, and incr…

Adenomyosis (AM), a gynecological disorder that severely affects female reproductive health. AM-associated macrophage (AAM) polarization-induced epithelial-mesenchymal transition (EMT) is a key driver of AM progression. In this study, we in…

BACKGROUND: An increasing number of studies have reported noteworthy health risks associated with dermal exposure to volatile organic compounds (VOCs) from feminine hygiene products (FHPs). OBJECTIVES: This study sought to address the gap …

In the field of treatment and prevention of immune-related bone diseases, significant challenges persist, necessitating the urgent exploration of new and effective treatment methods. However, most existing Mendelian randomization (MR) studi…

BACKGROUND: The prevention, management, and treatment of female cancers among women of childbearing age (WCBA) are crucial strategies for achieving the objectives outlined in the World Health Organization (WHO) Global Breast Cancer Initiati…

BACKGROUND: The human body's intestinal microbiota is a vital "organ" that coexists with it and is intimately linked to both human health and illness. Human intestinal microbiota and its metabolites are a crucial component in the developmen…

BACKGROUND: Chat-Generative Pretrained Transformer (ChatGPT) has proven its value in medical information acquisition and perioperative education. This study aimed to evaluate correlated factors to explore the value of ChatGPT in patient com…

CXC chemokine ligand 8 (CXCL8) has emerged as a critical mediator in tumorigenesis. This study aims to elucidate the role of CXCL8 in the initiation and progression of papillary thyroid carcinoma (PTC). Comprehensive bioinformatic analyses …

AIMS: Mesonephric-like adenocarcinoma (MLA) of the endometrium or ovary is a rare but distinct endometrial carcinoma which has a combination of characteristic morphological, immunohistochemical (IHC) and molecular features. SOX17 has been r…

BACKGROUND: Signet ring cell carcinoma originating from the appendix is extremely rare, and the lack of specific clinical symptoms and imaging features makes preoperative diagnosis particularly challenging. CASE SUMMARY: We report a case o…

BACKGROUND: The incidence of endometriosis is rising, particularly among younger populations, yet current diagnostic and therapeutic approaches remain limited. This highlights the urgent need for novel diagnostic tools and effective treatme…

BACKGROUND AND AIMS: Laparoscopic cholecystectomy (LC) often causes significant postoperative pain. While low-pressure pneumoperitoneum (8 mmHg) may reduce pain, optimal patient selection remains unclear. This trial compared pain outcomes b…

OBJECTIVE: To evaluate whether the timing of adenomyomectomy within the menstrual cycle influences outcomes in patients with adenomyosis, and to assess whether surgery performed during the secretory phase offers clinical advantages over the…