Correction: Macrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis

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AI-generated summary by claude@2026-06+body, 2026-06-13

This correction clarifies that macrophage-derived IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis by correcting mislabeled Western blot bands and statistical chart discrepancies.

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This corrigendum reports errors in a previously published Cell Death and Disease study on macrophage-derived IL-33/ST2 signaling and ferroptosis in endometriosis, specifically an image-labeling mix-up in Western blot bands (p-p38 mistakenly labeled as JNK) and a discrepancy between gel images and the quantitative statistics in Figure 6B. The authors state they corrected the mislabeled band by substituting the appropriate JNK band images and recalculated grayscale values from the original gels to update the statistical analysis and figure. They further clarify that recombinant IL-33 (rIL-33) suppressed phosphorylation of both P38 MAPK and JNK, with Western blot results showing downregulation of p-JNK/total JNK and p-p38/total p38 ratios in eESCs, and they explicitly state the corrections do not alter the study’s results or conclusions. This paper is centrally about endometriosis—specifically, macrophage-derived IL-33/ST2 inhibits ferroptosis via the ATF3/SLC7A11 axis.

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CORRECTION OPEN Correction: Macrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis Qiong Wu, Zongwen Liang, Jing Jiang, Xiaoming Feng, Jinming Liu, Zongfeng Zhang , Honglin Wang, Ning Wang, Yanling Gou, Zhi Li and Yingying Cao © The Author(s) 2025 Cell Death and Disease (2025) 16:212 ; https://doi.org/10.1038/s41419-025-07484-5 Correction to: Cell Death and Disease https://doi.org/10.1038/ s41419-023-06182-4, published online 11 October 2023 In this article the following mistakes have been identi fied: 1. JNK Bands Error: During the image preparation process, the p-p38 (phosphorylated p38) band was mistakenly labeled as JNK. This mislabeling led to the incorrect representation of the displayed band, potentially causing confusion in data interpretation. The authors have corrected this by replacing the mislabeled band with the appropriate JNK band images that accurately correspond to the p-JNK band images. 2. Statistical Chart Discrepancy: A discrepancy was identi fied between the statistical chart and the gel images in Figure 6B, which arose from an oversight during figures prepara- tion. The authors have recalculated the grayscale values from the gel images and conducted a new quantitative analysis. The revised statistical data has been incorporated into the updated figure. These corrections do not alter the results or conclusions of this study. All authors have reviewed and agreed to this corrigendum and express their gratitude to the Editor of Cell Death & Disease for providing the opportunity to address these issues. Finally, the authors sincerely apologize to the readership for any inconve- nience these errors may have caused. Original Figure 6 www.nature.com/cddis Official journal of CDDpress 1234567890();,: Corrected Figure 6 We further investigated the effects of rIL-33 on the P38 MAPK/JNK signaling pathway. Western blot images showed that after treatment with recombinant protein IL-33, the ratio of phosphory- lated modi fied JNK (p-JNK) to total JNK protein in eESCs was downregulated and the ratio of phosphorylated p38 (p-p38) to total p38 protein is downregulated. Intriguingly, our findings revealed that treatment with rIL-33 suppressed the phosphoryla- tion of both P38 MAPK and JNK (Fig. 6B). The original article has been corrected. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article ’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http:// creativecommons.org/licenses/by/4.0/. © The Author(s) 2025 Q. Wu et al. 2 Cell Death and Disease (2025) 16:212

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