Johan Smitz

ORCID: 0000-0002-5857-6542 · 14 papers in corpus
rct 2024
Reproductive medicine and biology ·doi:10.1002/rmb2.12587

PURPOSE: This study investigated the differences in the maturation rate of single versus grouped cumulus-oocyte complexes (COCs) culture methods for capacitation in vitro maturation (CAPA-IVM) in women with polycystic ovary syndrome (PCOS).…

rct 2020
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-019-01677-6

PURPOSE: Standard oocyte in vitro maturation (IVM) usually results in lower pregnancy rates than in vitro fertilization (IVF). IVM preceded by a prematuration step improves the acquisition of oocyte developmental competence and can enhance …

review 2020
Antioxidants & redox signaling ·doi:10.1089/ars.2019.7984

Significance: Four decades have passed since the first successful human embryo conceived from a fertilization in vitro. Despite all advances, success rates in assisted reproduction techniques still remain unsatisfactory and it is well estab…

rct 2019
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-019-01551-5

PURPOSE: To investigate the effectiveness of a biphasic IVM culture strategy at improving IVM outcomes in oocytes from small follicles (< 6 mm) compared with routine Standard IVM in patients with polycystic ovaries. METHODS: This prospecti…

nonrandomized-trial 2019
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-018-01398-2

PURPOSE: Clinical pregnancy rate after IVF with eSET stagnates between 30 and 40%. In order to increase pregnancy and live birth rates, multiple embryo transfer is still common practice. Providing additional non-invasive tools to choose the…

review 2014
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.3109/09513590.2013.859670

Luteinizing hormone (LH) and human chorionic gonadotropin (hCG) are integral components of the hypothalamic-pituitary-gonadal axis, which controls sexual maturation and functionality. In the absence of signaling through their shared recepto…

observational 2013
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.3109/09513590.2012.705379

The aim of this retrospective study was to investigate the impact of endogenous and exogenous luteinizing hormone (LH) activity on treatment outcome, when taking into consideration potential confounding variables. Data were derived from IVF…

other 2013
PloS one ·doi:10.1371/journal.pone.0054226

Cumulus cell (CC) gene expression is being explored as an additional method to morphological scoring to choose the embryo with the highest chance to pregnancy. In 47 ICSI patients with single embryo transfer (SET), from which individual CC …

rct 2012
Human reproduction (Oxford, England) ·doi:10.1093/humrep/des101

BACKGROUND: This study evaluated the predictive value of serum and follicular fluid (FF) concentrations of anti-Müllerian hormone (AMH) with respect to treatment outcome variables in an IVF cycle. METHODS: A retrospective analysis was perf…

2011
·doi:10.1017/cbo9780511734755.018

This chapter focuses on the non-invasive approaches which largely concentrate on proteomics analyses. Proteins are generated from the genome with signal sequences that direct them to the cell membrane or are secreted in the extracellular en…

2011
·doi:10.1093/humrep/26.s1.80
observational 2000
Human Reproduction ·doi:10.1093/humrep/15.7.1435

This study was designed to determine the effects of a vaginal micronized progesterone preparation on bleeding patterns and pregnancy outcomes after in-vitro fertilization and intracytoplasmic sperm injection (IVF-ICSI). The study population…

other 1995
Human Reproduction ·doi:10.1093/oxfordjournals.humrep.a136308

The objective of our study was to establish the most adequate ovarian stimulation regimen for assisted procreation in endometriotic patients. It consisted of a retrospective analysis comparing the use of the gonadotrophin-releasing hormone …

nonrandomized-trial 1987
Human Reproduction ·doi:10.1093/oxfordjournals.humrep.a136515

The results of 100 gamete intra-Fallopian transfer (GIFT) procedures to treat persistent infertility are reported. Twenty-four pregnancies were achieved, of these six aborted, two were extra-uterine, two stillbirths occurred and nine patien…