Chang CM

No ORCID on file · 9 papers in corpus · active 2010-2026

Study types

  • article 2
  • case-report 1
  • meta-analysis 1
  • other 1
  • review 1

Condition tags

  • endometriosis 6
  • infertility 2
  • endometrioma 1
  • adenomyosis 1
other 2026
Integrative gene ontology-driven analysis of the eutopic endometrium reveals key dysregulated functionomes and pathways in endometriosis
Journal of the Chinese Medical Association : JCMA ·doi:10.1097/JCMA.0000000000001382

BACKGROUND: Endometriosis is a chronic estrogen-dependent inflammatory disorder associated with pelvic pain, infertility, and an increased risk of endometriosis-associated ovarian cancer. Despite extensive research, its molecular mechanisms…

case-report 2020
Endometriosis-associated epithelial ovarian cancer: Primary synchronous different cellular type on each ovary
Taiwanese journal of obstetrics & gynecology ·doi:10.1016/j.tjog.2020.03.024

OBJECTIVE: Endometriosis-associated epithelial ovarian cancer (EOC) is a specific category of EOC, containing either endometrioid or clear cell carcinoma subtype. The characteristic of endometriosis-associated EOC includes an early stage at…

review 2020
The recent progress and therapy in endometriosis-associated ovarian cancer
Journal of the Chinese Medical Association : JCMA ·doi:10.1097/jcma.0000000000000262

Endometriosis-associated ovarian cancers (EAOCs) including endometrioid and clear cell ovarian carcinoma are subgroups of epithelial ovarian carcinomas (EOCs), which is generally acknowledged as the most lethal gynecological malignancy. End…

2018
Key Immunological Functions Involved in the Progression of Epithelial Ovarian Serous Carcinoma Discovered by the Gene Ontology-Based Immunofunctionome Analysis.
International journal of molecular sciences ·doi:10.3390/ijms19113311

Serous carcinoma (SC) is the most common and lethal subtype of epithelial ovarian carcinoma; immunotherapy is a potential treatment for SC, however, the global immunological functions of SC as well as their change during the progression of …

meta-analysis 2017
Discovering the Deregulated Molecular Functions Involved in Malignant Transformation of Endometriosis to Endometriosis-Associated Ovarian Carcinoma Using a Data-Driven, Function-Based Analysis
International journal of molecular sciences ·doi:10.3390/ijms18112345

The clinical characteristics of clear cell carcinoma (CCC) and endometrioid carcinoma EC) are concomitant with endometriosis (ES), which leads to the postulation of malignant transformation of ES to endometriosis-associated ovarian carcinom…

2017
Electronegative LDL-mediated cardiac electrical remodeling in a rat model of chronic kidney disease.
Scientific reports ·doi:10.1038/srep40676

The mechanisms underlying chronic kidney disease (CKD)-associated higher risks for life-threatening ventricular tachyarrhythmias remain poorly understood. In rats subjected to unilateral nephrectomy (UNx), we examined cardiac electrophysiol…

article 2017
Integrating the dysregulated inflammasome-based molecular functionome in the malignant transformation of endometriosis-associated ovarian carcinoma
Oncotarget ·doi:10.18632/oncotarget.23364

The coexistence of endometriosis (ES) with ovarian clear cell carcinoma (CCC) or endometrioid carcinoma (EC) suggested that malignant transformation of ES leads to endometriosis associated ovarian carcinoma (EAOC). However, there is still l…

2016
Gene Set-Based Integrative Analysis Revealing Two Distinct Functional Regulation Patterns in Four Common Subtypes of Epithelial Ovarian Cancer.
International journal of molecular sciences ·doi:10.3390/ijms17081272

Clear cell (CCC), endometrioid (EC), mucinous (MC) and high-grade serous carcinoma (SC) are the four most common subtypes of epithelial ovarian carcinoma (EOC). The widely accepted dualistic model of ovarian carcinogenesis divided EOCs into…

article 2010
Suppression of migratory/invasive ability and induction of apoptosis in adenomyosis-derived mesenchymal stem cells by cyclooxygenase-2 inhibitors
Fertility and sterility ·doi:10.1016/j.fertnstert.2010.01.070

ObjectiveTo investigate if stem or progenitor cells are found in adenomyosis and to characterize the role of cyclooxygenase-2 (COX-2) in adenomyosis-derived mesenchymal stem cell (AMSC)-related pathogenesis of adenomyosis.DesignExperimental…