Patrícia Zancan

No ORCID on file · 3 papers in corpus · active 2018-2023

Study types

  • article 2
  • other 1

Condition tags

  • endometriosis 3
article 2023
Clotrimazole is effective, safe and tolerable for the treatment of endometriosis and functions by downregulating inducible nitric oxide synthase and modulating oxidative stress biomarkers
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2023.111883

This study investigated the mechanism of action of clotrimazole (CTZ) and its adverse effects in a model of endometriosis. After autologous endometrial implantation, 18 rats were randomized into two treatment groups: 200 mg/kg CTZ or vehicl…

article 2020
Clotrimazole reduces endometriosis and the estrogen concentration by downregulating aromatase
Reproduction (Cambridge, England) ·doi:10.1530/rep-19-0502

This study aimed to analyse the effects of clotrimazole (CTZ) on estrogen production pathway in endometriosis progression. Experimental endometriosis was induced by autologous transplantation in female Wistar rats, and then the rats were tr…

other 2018
Clotrimazole is effective for the regression of endometriotic implants in a Wistar rat experimental model of endometriosis
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2018.04.005

The present work aimed to evaluate molecular, angiogenic and inflammatory changes induced by clotrimazole (CTZ) on endometriosis lesions. For this, thirty female Wistar rats with surgically implanted autologous endometrium were treated with…