Karen H Lu

No ORCID on file · 21 papers in corpus · active 2012-2026

Study types

  • preprint 14
  • article 3
  • other 3
  • review 1

Condition tags

  • endometriosis 6
review 2026
Mesonephric-like Adenocarcinoma (MLA) Diagnostic Criteria and Controversies: Perspectives and Guidance From Pathologists in the MLA Consortium
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists ·doi:10.1097/PGP.0000000000001150

Mesonephric-like adenocarcinoma (MLA) is a rare and aggressive gynecologic malignancy that has only been recognized in the last decade. It arises in the endometrium, ovaries, and other extrauterine sites (often in association with endometri…

article 2024
Abstract B067: Omentin: A novel immune modulator in the pro-inflammatory omental microenvironment of high-grade serous ovarian cancer
·doi:10.1158/1538-7445.ovarian23-b067

Abstract Advanced stage high grade serous ovarian cancer (HGSC) metastasizes preferentially to the omentum, which is a well-vascularized fold of peritoneal tissue covered by mesothelial cells and a major site of intra-abdominal fat accumula…

other 2024
Clinical and Genomic Landscape of RAS Mutations in Gynecologic Cancers
Clinical cancer research : an official journal of the American Association for Cancer Research ·doi:10.1158/1078-0432.CCR-23-2819

PURPOSE: We aimed to describe RAS mutations in gynecologic cancers as they relate to clinicopathologic and genomic features, survival, and therapeutic implications. EXPERIMENTAL DESIGN: Gynecologic cancers with available somatic molecular …

preprint 2023
Supplementary Figure 1 from Omental Adipose Tissue–Derived Stromal Cells Promote Vascularization and Growth of Endometrial Tumors
·doi:10.1158/1078-0432.22443752

PDF file - 387K, Three-lineage differentiation of O-ASC.

preprint 2023
Supplementary Figure 1 from Omental Adipose Tissue–Derived Stromal Cells Promote Vascularization and Growth of Endometrial Tumors
·doi:10.1158/1078-0432.22443752.v1

PDF file - 387K, Three-lineage differentiation of O-ASC.

preprint 2023
Supplementary Figure 2 from Omental Adipose Tissue–Derived Stromal Cells Promote Vascularization and Growth of Endometrial Tumors
·doi:10.1158/1078-0432.22443749

PDF file - 678K, O-ASC do not co-localize with CD31 positive endothelial cells.

preprint 2023
Supplementary Figure 2 from Omental Adipose Tissue–Derived Stromal Cells Promote Vascularization and Growth of Endometrial Tumors
·doi:10.1158/1078-0432.22443749.v1

PDF file - 678K, O-ASC do not co-localize with CD31 positive endothelial cells.

preprint 2023
Supplementary Figure 3 from Omental Adipose Tissue–Derived Stromal Cells Promote Vascularization and Growth of Endometrial Tumors
·doi:10.1158/1078-0432.22443746.v1

PDF file - 202K, Quantification of histological and immunofluorescence tissue analysis.

preprint 2023
Supplementary Figure 3 from Omental Adipose Tissue–Derived Stromal Cells Promote Vascularization and Growth of Endometrial Tumors
·doi:10.1158/1078-0432.22443746

PDF file - 202K, Quantification of histological and immunofluorescence tissue analysis.

preprint 2023
Supplementary Figure 4 from Omental Adipose Tissue–Derived Stromal Cells Promote Vascularization and Growth of Endometrial Tumors
·doi:10.1158/1078-0432.22443743

PDF file - 139K, Endometrial Hec1a cancer cell proliferation in co-culture with OSC, MSC, ASC and WI38 fibroblasts.

preprint 2023
Supplementary Figure 4 from Omental Adipose Tissue–Derived Stromal Cells Promote Vascularization and Growth of Endometrial Tumors
·doi:10.1158/1078-0432.22443743.v1

PDF file - 139K, Endometrial Hec1a cancer cell proliferation in co-culture with OSC, MSC, ASC and WI38 fibroblasts.

preprint 2023
Supplementary Figure 6 from Omental Adipose Tissue–Derived Stromal Cells Promote Vascularization and Growth of Endometrial Tumors
·doi:10.1158/1078-0432.22443737.v1

PDF file - 99K, Migration of stromal cells in response to Hec1a conditioned media.

preprint 2023
Supplementary Figure 6 from Omental Adipose Tissue–Derived Stromal Cells Promote Vascularization and Growth of Endometrial Tumors
·doi:10.1158/1078-0432.22443737

PDF file - 99K, Migration of stromal cells in response to Hec1a conditioned media.

preprint 2023
Supplementary Figure 7 from Omental Adipose Tissue–Derived Stromal Cells Promote Vascularization and Growth of Endometrial Tumors
·doi:10.1158/1078-0432.22443734.v1

PDF file - 281K, Hec1a secrete IL8 and CXCL1.

preprint 2023
Supplementary Figure 7 from Omental Adipose Tissue–Derived Stromal Cells Promote Vascularization and Growth of Endometrial Tumors
·doi:10.1158/1078-0432.22443734

PDF file - 281K, Hec1a secrete IL8 and CXCL1.

preprint 2023
Supplementary Figure 8 from Omental Adipose Tissue–Derived Stromal Cells Promote Vascularization and Growth of Endometrial Tumors
·doi:10.1158/1078-0432.22443731.v1

PDF file - 1.0MB, Expression of IL8 / CXCL1 receptors in mesenchymal cells.

preprint 2023
Supplementary Figure 8 from Omental Adipose Tissue–Derived Stromal Cells Promote Vascularization and Growth of Endometrial Tumors
·doi:10.1158/1078-0432.22443731

PDF file - 1.0MB, Expression of IL8 / CXCL1 receptors in mesenchymal cells.

other 2015
Phase II study of everolimus and letrozole in patients with recurrent endometrial carcinoma
Journal of clinical oncology : official journal of the American Society of Clinical Oncology ·doi:10.1200/JCO.2014.58.3401

PURPOSE: The phosphoinositol-3 kinase (PI3K) pathway is frequently dysregulated in endometrial cancer (EC). Hormonal manipulation leads to response in some patients with EC, but resistance derived from PI3K pathway activation has been docum…

article 2015
Shared genetics underlying epidemiological association between endometriosis and ovarian cancer

Epidemiological studies have demonstrated associations between endometriosis and certain histotypes of ovarian cancer, including clear cell, low-grade serous and endometrioid carcinomas. We aimed to determine whether the observed associatio…

article 2015
Shared genetics underlying epidemiological association between endometriosis and ovarian cancer
Human molecular genetics ·doi:10.1093/hmg/ddv306

Epidemiological studies have demonstrated associations between endometriosis and certain histotypes of ovarian cancer, including clear cell, low-grade serous and endometrioid carcinomas. We aimed to determine whether the observed associatio…

other 2012
Serum HE4 levels are less frequently elevated than CA125 in women with benign gynecologic disorders
American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2011.12.029

OBJECTIVE: The human epididymis protein 4 (HE4) is a novel biomarker for ovarian cancer. This study measured the HE4 and CA125 levels in women with benign gynecological disorders. STUDY DESIGN: Sera were obtained from women prior to surger…