Yamamoto T — Endo Lab

other 1993

[Allelic losses of tumor suppressor gene on chromosome 17 in ovarian cancer]

Nihon Sanka Fujinka Gakkai zasshi

Twenty-one human ovarian epithelial carcinomas (13 serous, 3 mucinous, 2 endometrioid and 3 clear cell type) were examined for allelic losses of p53 tumor suppressor gene, pYNZ22 or pTHH59 on chromosome 17. High-molecular-weight DNA was ext…

article 1993

Evidence for estrogen synthesis in adenomyotic tissues

American journal of obstetrics and gynecology ·doi:10.1016/0002-9378(93)90654-2

ObjectiveTo investigate steroidogenesis in eutopic and ectopic endometrial tissues in adenomyosis.Study designAromatase and estrone sulfatase activities were determined by anion-exchange resin column chromatography, thin-layer chromatograph…

article 1990

Inhibitory effect of a new androstenedione derivative, 14α-hydroxy-4-androstene-3,6,17-trione (14α-OHAT) on aromatase activity of human uterine tumors

Journal of steroid biochemistry ·doi:10.1016/0022-4731(90)90167-q

The development of human uterine estrogen-dependent tumors is considered to be closely related to estrogen biosynthesis. This study examined whether or not 14 alpha-hydroxy-4-androstene-3,6,17-trione (14 alpha-OHAT), a new 4-androstene-3, 1…

article 1989

Estrogen biosynthesis in human uterine adenomyosis

Acta endocrinologica ·doi:10.1530/acta.0.1210259

Estrogen biosynthesis (aromatase activity) was investigated in human adenomyosis tissue and compared with that of the normal myometrium, endometrium, and endometrial cancer tissues. Homogenates were incubated with [1,2,6,7-3H]androstenedion…

article 1988

[A case of stromal endometriosis (endolymphatic stromal myosis) in the effective treatment with progestogen].

Nihon Sanka Fujinka Gakkai zasshi