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- article 4
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- endometriosis 4
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BACKGROUND: Dysregulated hyaluronic acid (HA) metabolism has been shown to be implicated in several pathologies including endometriosis. 4-Methylumbelliferone (4MU) is an HA synthesis inhibitor with proven antitumour activity. In this study…
Research questionDoes resveratrol exert a potent inhibitory effect on the development of endometriosis by interfering with some pivotal processes?DesignIn-vitro cultures of primary endometriotic stromal cells, immortalized endometrial strom…
< 0.01, respectively). These results are promising and reveal that urolithins A and B, separately, have a beneficial effect on the overall endometriotic growth without affecting the body weight or estrous cycle.
Based on the inflammatory nature and hormone-dependency of endometriosis, PI3K/AKT signaling appears to influence its progression. Could the endometriosis stages be linked to differential changes in PI3K/AKT pathway regulation? The objectiv…