Keith B Isaacson
No ORCID on file
· 9 papers in corpus
review
2022
PURPOSE OF REVIEW: Adenomyosis has recently been associated with infertility. Relief of bleeding and pain has been demonstrated with medical and surgical therapy. Less is known about reproductive outcomes after treatment. RECENT FINDINGS: …
other
2021
STUDY OBJECTIVE: To assess the feasibility of a noncontact radio sensor as an objective measurement tool to study postoperative recovery from endometriosis surgery. DESIGN: Prospective cohort pilot study. SETTING: Center for minimally inv…
review
2020
A Systematic Review of Adenomyosis: It Is Time to Reassess What We Thought We Knew about the Disease
ObjectiveTo summarize and update our current knowledge regarding adenomyosis diagnosis, prevalence, and symptoms.Data sourcesSystematic review of PubMed between January 1972 and April 2020. Search strategy included: "adenomyosis [MeSH Terms…
article
2020
PROBLEM: To compare inflammatory- and immune-associated peritoneal cytokines of adolescents and adults with and without endometriosis. METHODS OF STUDY: In a nested case-control study in multiple university-affiliated scientific centers, te…
other
2019
Metalloproteinases (MMPs) are zinc-dependent endopeptidases that cleave various proteins to regulate normal and diseased cellular functions, and as such, they play significant roles in human tissue development, homeostasis, and the pathogen…
article
2017
ObjectiveOur aim was to characterize peritoneal cytokine profiles in patients with infertility, with and without endometriosis, to illuminate potential differences in immune profiles that may reflect mechanistic differences between these tw…
article
2014
Molecular Network Analysis of Endometriosis Reveals a Role for c-Jun–Regulated Macrophage Activation
Clinical management of endometriosis is limited by the complex relationship between symptom severity, heterogeneous surgical presentation, and variability in clinical outcomes. As a complement to visual classification schemes, molecular pro…
article
2012
As principal degrading enzymes of the extracellular matrix, metalloproteinases (MPs) contribute to various pathologies and represent a family of promising drug targets and biomarker candidates. However, multiple proteases and endogenous inh…
article
2002
ObjectiveTo explore the role of G-protein coupled signaling pathways in activation of macrophage migration in endometriosis stages I and II.DesignCase controlled study.SettingUniversity hospital.Patient(s)Fifteen patients undergoing laparos…