Le Xu
No ORCID on file
· 7 papers in corpus
· active 2023-2026
Study types
- other 4
- article 3
Condition tags
- endometriosis 6
- endometrioma 1
- adenomyosis 1
Top journals
Frequent coauthors
- Guoyun Wang 7
- Xue Jiao 6
- Ming Yuan 6
- Shuang Wang 5
- Xiaoyu Dong 4
- Qianhui Ren 4
- Xiaoxuan Liu 2
- Yufei Huang 2
- Shumin Yan 2
- Zhaoyang Zhong 2
other
2026
Endometriosis (EM) is driven by immune dysregulation and macrophage dysfunction, yet the underlying mechanisms remain unclear. Here, metabolomic profiling revealed excessive itaconate accumulation in EM lesions, primarily due to elevated ci…
other
2026
PURPOSE: Endometriosis (EM) is a chronic inflammatory gynecological disorder characterized by ectopic endometrial-like lesions, where aberrant angiogenesis is a hallmark driving lesion establishment and progression. However, the transcripti…
article
2025
BACKGROUND: Endometriosis (EM) exhibits localised iron overload. However, the contribution of ferroptosis to EM pathogenesis remains unclear. We investigated how iron overload affects CD8⁺ T cell immune function and the underlying ferroptot…
other
2024
The pathogenesis of adenomyosis is closely related to the epithelial-mesenchymal transition and macrophages. MicroRNAs have been extensively investigated in relation to the epithelial-mesenchymal transition in a range of malignancies. Howev…
other
2024
Endometriosis diagnosis is usually delayed. The gold standard for diagnosing endometriosis is laparoscopy, which is invasive and accompanied by several risks. Currently, there are no effective non-invasive biomarkers for diagnosing endometr…
article
2023
Ferroptosis is an iron-dependent programmed cell death process characterized by the accumulation of lethal oxidative damage. Localized iron overload is a unique clinical phenomenon in ovarian endometriosis (EM). However, the role and mechan…
article
2023
The development of endometriosis is closely linked to macrophages, and the type M1 macrophage has been hypothesized to play an inhibitory role in its progression. Escherichia coli induces macrophage polarization toward M1 in numerous diseas…