Noriyuki Takai

No ORCID on file · 12 papers in corpus · active 1999-2016

Study types

  • article 10
  • review 2

Condition tags

  • endometriosis 12
  • adenomyosis 1
article 2016
studyfor the treatment of endometriosis: an in vitro B inhibitor BAY κ Application of the nuclear factor-
article 2012
Mechanism Underlying the Pathogenesis of Endometriosis Aberrant Expression of Apoptosis-Related Molecules in Endometriosis : A Possible
review 2011
Aberrant DNA methylation status of endometriosis: Epigenetics as the pathogenesis, biomarker and therapeutic target
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/j.1447-0756.2011.01663.x

Endometriosis, a common, benign, estrogen-dependent disease affecting 3-10% of women of reproductive age, is characterized by the ectopic growth of endometrial tissue that is found primarily in the peritoneum, ovaries and rectovaginal septu…

review 2011
Aberrant expression of apoptosis-related molecules in endometriosis: a possible mechanism underlying the pathogenesis of endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719110392059

Endometriosis, a disease affecting 3% to 10% of women of reproductive age, is characterized by the ectopic growth of endometrial tissue under the influence of estrogen. It is also becoming recognized as a condition in which ectopic endometr…

article 2011
Application of the histone deacetylase inhibitors for the treatment of endometriosis: histone modifications as pathogenesis and novel therapeutic target
Human Reproduction ·doi:10.1093/humrep/der203

BACKGROUND: Accumulating evidence suggests that various epigenetic aberrations play definite roles in the pathogenesis of endometriosis. We investigated the histone acetylation status in endometriosis and the application of the histone deac…

article 2008
Bowel obstruction due to endometriosis in the rectovaginal septum.
Clinical and experimental obstetrics & gynecology

It is very rare that endometriotic lesions in the rectovaginal septum cause ileus. We report a case of bowel obstruction due to endometriotic lesions in the rectovaginal septum in a 22-year-old woman whose barium enema presented with apple-…

article 2007
The Role of Apoptotic Dysfunction in the Pathogenesis of Endometriosis
·doi:10.2174/1573404810703020113

Endometriosis, a disease affecting 3-10% of women of reproductive age, is characterized by the ectopic growth of endometrial tissue. Increasingly, endometriosis is also becoming recognized as a condition in which ectopic endometrial cells e…

article 2006
Application of the nuclear factor-κB inhibitor BAY 11-7085 for the treatment of endometriosis: an in vitro study
American journal of physiology. Endocrinology and metabolism ·doi:10.1152/ajpendo.00135.2006

Most of the current medical treatments for endometriosis aim to downregulate estrogen activity. However, a high recurrence rate after medical treatment has been the most significant problem. BAY 11-7085, a soluble inhibitor of NK-kappaB act…

article 2006
β-Hydroxyisovalerylshikonin induces apoptosis and G0/G1 cell-cycle arrest of endometriotic stromal cells: a preliminary in vitro study
Human Reproduction ·doi:10.1093/humrep/del270

BACKGROUND: Most of the current medical treatments for endometriosis aim to down-regulate the estrogen activity. However, a high recurrence rate after medical treatments has been the most significant problem. Beta-hydroxyisovalerylshikonin …

article 2005
Bufalin induces apoptosis and the G0/G1 cell cycle arrest of endometriotic stromal cells: a promising agent for the treatment of endometriosis
Molecular human reproduction ·doi:10.1093/molehr/gah249

Most of the current medical treatments for endometriosis aim to down-regulate the estrogen activity. However, a high recurrence rate after medical treatments has been the most significant problem. Bufalin is a major digoxin-like immunoreact…

article 2004
Endometriotic cells are resistant to interferon-γ-induced cell growth inhibition and apoptosis: a possible mechanism involved in the pathogenesis of endometriosis
Molecular human reproduction ·doi:10.1093/molehr/gah133

In order to evaluate the involvement of cell proliferation and apoptosis in the pathogenesis of endometriosis, we investigated the effects of interferon-gamma (IFN-gamma) on cell growth inhibition and apoptosis of cultured ovarian endometri…

article 1999
Endometrioid Adenocarcinoma Arising from Adenomyosis
Gynecologic and obstetric investigation ·doi:10.1159/000010139

In spite of many references to carcinoma arising from endometriosis at extrauterine sites, there are few documented cases of carcinoma developing in association with adenomyosis. We present 2 rare cases of adenocarcinoma arising from adenom…