Geirsson RT

Endometriosis is a chronic condition causing menstrual pain, irregular bleeding and infertility among women. Although usually in the pelvis, it can manifest in atypical places. We describe a 39-year old woman with a previous endometriosis d…

Uterine leiomyomas are common benign tumors of the myometrium. We performed a meta-analysis of two genome-wide association studies of leiomyoma in European women (16,595 cases and 523,330 controls), uncovering 21 variants at 16 loci that as…

Endometriosis is a heritable hormone-dependent gynecological disorder, associated with severe pelvic pain and reduced fertility; however, its molecular mechanisms remain largely unknown. Here we perform a meta-analysis of 11 genome-wide ass…

We conducted a genome-wide association scan (GWAS) of endometriosis using 25.5 million sequence variants detected through whole-genome sequencing (WGS) of 8,453 Icelanders and imputed into 1,840 cases and 129,016 control women, followed by …

At the end of the month of May, colleagues in the Nordic countries and some others from further afield gather for the fourth time to discuss endometriosis, a disease that may for many women spoil years of what should be the best time of lif…

From the Editorial Board we wish all who read this a good and successful year 2013, – it is our official 92nd publication year. We urge all our subscribers in the Nordic countries to register for the online version of the journal, if they h…

We are coming into the autumn months now, with the days getting shorter at northerly latitudes, and it may be a good time to not let go of this issue of the journal just yet, but now that you have opened it anyway to sit down and run throug…

The annual incidence of pelvic endometriosis among women aged 15-49 years and up to age 69 years was ascertained for the Icelandic population between 1981 and 2000 by using Iceland's extensive record linkage systems. Comprehensive, state-fi…

This month's issue is largely an obstetric one. Over the publication year we have a more or less even distribution of gynecology and obstetrics, but it can happen that an overweight of one or the other is created among accepted articles, ju…

ObjectiveTo investigate quantitative aberrations involving p53 copy numbers in eutopic endometrial and endometriotic tissue from two populations.DesignComparative analysis of normal and diseased tissue.SettingTissue specimens collected in I…

BACKGROUND: Endometriosis is known to cluster within nuclear families. The extent of familial clustering can be evaluated in Iceland with its large population-based genealogical database. METHODS AND RESULTS: Applying several measures of f…

ObjectiveTo investigate a possible association between the carrier frequency of the N314D mutation in the galactose-1-phosphate uridyl transferase (GALT) gene and endometriosis and linkage to the short arm of chromosome 9, where the GALT ge…