Singh M

Ovarian cancer remains a highly lethal malignancy, with advanced-stage diagnosis, recurrence, and chemoresistance, thus limiting clinical outcomes. Traditional biomarkers such as CA-125, BRCA1/2 status, and histopathology offer only a parti…

BACKGROUND: Primary dysmenorrhea (PD) involves painful lower abdominal cramps during menstruation without pelvic pathology. Oxidative stress may contribute to PD pathogenesis. This study examined the correlation between oxidative stress mar…

There are a variety of benign and malignant indications for women that may cause a patient to seek fertility preservation counseling. Several benign conditions that may lead to early infertility include endometriosis, ovarian torsion, benig…

In vitro fertilization (IVF) is a groundbreaking assisted reproductive technology (ART) that has revolutionized fertility treatment since its inception in the late 20th century. First successfully performed by Dr. Robert Edwards and Dr. Pat…

INTRODUCTION: One in five women enters pregnancy with multiple long-term health conditions, which is associated with increased risks of adverse maternal and child outcomes. There is a lack of research exploring individuals' experiences of p…

BACKGROUND: Among women in the UK, over 186,000 new cancer diagnoses and around 78,000 cancer deaths occurred annually from 2017 to 2019. Evidence suggests that pregnancy complications are linked to mortality and morbidity risks in later li…

Introduction Abnormal uterine bleeding (AUB) is a common issue in gynecological practice and may require evaluation depending on the patient's age and clinical presentation. The aim of this study was to compare the diagnostic accuracy, samp…

BACKGROUND: Multimorbidity in pregnancy increases health risks to women and babies, and creates challenges for services. The aim of this study was to explore the prevalence and patterns of maternal multimorbidity in a UK population. METHOD…

Tuberculosis (TB) is a significant global health issue with India accounting for about 25% of the global TB burden. While TB primarily impacts the lungs, extrapulmonary cases are also common, particularly female genital TB (GTB) among young…

What makes this case noteworthy is the fact that this patient presented with breast cancer after receiving long-term hormone replacement therapy. She was placed on this therapy after a total abdominal hysterectomy for endometriosis. This wa…

Extracellular vesicles (EVs), a diverse group of cell-derived exocytosed particles, are pivotal in mediating intercellular communication due to their ability to selectively transfer biomolecules to specific cell types. EVs, composed of prot…

OBJECTIVE: To compare clinical outcomes between nonindicated intracytoplasmic sperm injection (ICSI) and conventional insemination. DESIGN: Autologous cycles performed from 2014-2017 were identified, excluding frozen oocyte cycles. Outcome…

Ovarian cancer poses a significant threat to patients in its advanced stages, often with limited treatment options available. In such cases, palliative management becomes the primary approach to maintaining a reasonable quality of life. The…

Primary clear cell adenocarcinoma (CCA) of the urinary bladder is a rare and aggressive malignancy. Few reports in the literature describe this presentation, as associated with malignant transformation of endometriosis. This case highlights…

N-acetylcysteine (NAC) has established use as an antidote for acetaminophen overdose and treatment for pulmonary conditions and nephropathy. It plays a role in regulating oxidative stress and interacting with various cytokines including IL-…

INTRODUCTION: Clinical reasoning (CR) is a complex skill enabling transition from clinical novice to expert decision maker. The Objective Structured Clinical Examination (OSCE) is widely used to evaluate clinical competency, though there is…

Broad ligament pregnancy is defined as gestation that grows in the space formed by anterior and posterior peritoneal folds of the broad ligament. We report a case of 30 years old lady admitted to our hospital with the diagnosis of gravida 2…

Abstract Objective The aim of this review is to analyse the patent filings and to systematize the main technological trends in patent protection for the diagnosis and therapeutics for Endometriosis. Patent literature has also been explore…

INTRODUCTION: One in five pregnant women has multiple pre-existing long-term conditions in the UK. Studies have shown that maternal multiple long-term conditions are associated with adverse outcomes. This observational study aims to compare…

OBJECTIVES: The aim of this study was to compare operative data and postoperative complications among nondescent vaginal hysterectomy (NDVH), laparoscopy-assisted vaginal hysterectomy (LAVH), and total laparoscopic hysterectomy (TLH) at a r…

Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2) infection is frequently associated with a wide range of persistent symptoms, now referred to as post-COVID-19 condition, or Long COVID. The objectives of this study were…

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is associated with a range of persistent symptoms impacting everyday functioning, known as post-COVID-19 condition or long COVID. We undertook a retrospective matched co…

Cervical agenesis is a rare congenital Mullerian anomaly. Its association with vaginal agenesis is further rare, reported in 39% of cases of cervical agenesis. The conventional treatment for this condition was hysterectomy. However, with ev…

We report a case of thoracic endometriosis syndrome (TES) presenting with a five-week history of progressive shortness of breath, cough, and wheezing. Investigations revealed a large, right-sided pleural effusion that was bloody on aspirati…

BACKGROUND: Abnormal uterine bleeding (AUB) is a common problem affecting the women of reproductive age group and may also have a significant impact on their physical, social, and emotional aspects directly affecting their quality of life. …