BackgroundFertility status is a marker of future health, and female infertility has been shown to be an important medical and social problem. Life's Essential 8 ("LE8") is a comprehensive cardiovascular health assessment proposed by the Ame…
Background/Objectives: Aromatase plays a crucial role in the conversion of androgens to oestrogens and is often overexpressed in hormone-dependent tumours, particularly breast cancer. [18F]BIBD-071, which has excellent binding affinity for …
ObjectiveWe aimed to explore the current research status and development trend of chronic pain treated with external therapies in traditional Chinese medicine (TCM) and to provide a reference for further research in this field.MethodsFrom t…
Central adiposity, measured by waist-to-hip ratio (WHR), is a modifiable risk factor for female infertility, yet its causal role remain underexplored. Combining observational data from National Health and Nutrition Examination Survey (N = 1…
RationaleWell-differentiated papillary mesothelial tumor (WDPMT) is an uncommon, slow-growing neoplasm that is often an incidental finding in the peritoneum of women of reproductive age. It can be misdiagnosed as malignant mesothelioma on r…
Advanced maternal age (AMA, ≥35 years) women undergoing assisted reproductive technology (ART) face reduced live birth rates (LBR) and remain a major clinical challenge. In a large randomized trial, Zishen Yutai Pill (ZYP) improved LBR in t…
ObjectiveThe aim of this study was to enhance the precision of categorization of endometrial lesions in ultrasound images via a data enhancement framework based on deep learning (DL), through addressing diagnostic accuracy challenges, contr…
Haiping Li,1,* Xuesong Wang,1,* Yu Wang,1 Yuanbo Gao,1 Xiaojun Zheng,1 Xifen Zhang,1 Xuxin Li,1 Xihui Zheng,1 Xisheng Fan,1,2 Guang Zuo,1 Yanfen She1,2 1College of Acupuncture-Moxibustion and Tuina, Hebei University of Chinese Medicine, Shi…
Haiping Li,1,* Xuesong Wang,1,* Yu Wang,1 Yuanbo Gao,1 Xiaojun Zheng,1 Xifen Zhang,1 Xuxin Li,1 Xihui Zheng,1 Xisheng Fan,1,2 Guang Zuo,1 Yanfen She1,2 1College of Acupuncture-Moxibustion and Tuina, Hebei University of Chinese Medicine, Shi…
Aldo-Keto Reductase Family 1 Member C3 (AKR1C3), also known as type 5 17β-hydroxysteroid dehydrogenase (17β-HSD5) or prostaglandin F (PGF) synthase, functions as a pivotal enzyme in androgen biosynthesis. It catalyzes the conversion of weak…
Li, Wangshu; Wang, Xiuying; Zhang, Xu; Sun, Shu; Feng, Jiuxiang; Aziz, Aziz ur Rehman PhD Author Information
Abstract Objective To explore factors related to dysmenorrhea in adenomyosis and construct a risk prediction model. Methods A cross-sectional survey involving 1636 adenomyosis patients from 37 hospitals nationwide (November 2019 - Februa…
BackgroundPrimary Sjögren syndrome (pSS) is often related to adverse neonatal outcomes. But it's currently controversial whether pSS has an adverse effect on female fertility and clinical pregnancy condition. More importantly, it's unclear …
Myocardial infarction (MI) results in cardiomyocyte necrosis and conductive system damage, leading to sudden cardiac death and heart failure. Studies have shown that conductive biomaterials can restore cardiac conduction, but cannot facilit…
BackgroundTo train highly qualified medical talent in 5-year programs and improve students' analytical and problem-solving abilities, it is necessary to change the traditional teaching method. This study introduces the combined teaching met…
PURPOSE: To evaluate the association between Composite Dietary Antioxidant Index (CDAI) and the risk of endometriosis (EM)-related rheumatoid arthritis (RA) in women of childbearing age. METHODS: Using the data from the National Health and…
Haiyang Hu, Xiaoxiao Wang, Yangsheng Ren, Tishuo Zhang, Lin Sun Department of Gynecology, Affiliated Hospital of Jining Medical University, Jining, Shandong, 272029, People’s Republic of ChinaCorrespondence: Lin Sun Department of Gynecology…
Pancreatic adenocarcinoma (PAAD) is a frequent malignant tumor in the pancreas. The incomplete understanding of cancer etiology and pathogenesis, as well as the limitations in early detection and diagnostic methods, have created an urgent n…
Abstract Background Numerous investigations have demonstrated the implication of endoplasmic reticulum stress (ERS) in the etiology of endometriosis. Employing bioinformatics methodologies, we conducted an analysis to ascertain the particip…
PurposeWith the rapid advancement of time-lapse culture and artificial intelligence (AI) technologies for embryo screening, pregnancy rates in assisted reproductive technology (ART) have significantly improved. However, clinical pregnancy r…
It is unusual for young patients without any underlying diseases to experience sudden cerebral infarction and heart failure. Here, we report a rare case of a 28-year-old female patient who presented with chest tightness and dizziness. Left …
BackgroundThe causal impact of lipid-lowering drugs on ovarian cancer (OC) and cervical cancer (CC) has received considerable attention, but its causal relationship is still a subject of debate. Hence, the objective of this study is to eval…
PurposeObservational studies and clinical validation have suggested a link between thyroid dysfunction and an elevated ovarian cancer (OC) risk. However, whether this association indicates a cause-and-effect relationship remains uncertain. …
Study questionDoes the downregulation of cell division cycle 42 (CDC42) protein in endometrial stroma lead to endometrial senescence in patients with recurrent implantation failure (RIF), and what is the potential mechanism?Summary answerCD…