Akshintala VS

No ORCID on file · 4 papers in corpus · active 2022-2026
2026
Chronic Pancreatitis: Mechanisms of Inflammation, Pathways of Progression and Emerging Therapeutic Strategies.
Gastroenterology ·doi:10.1053/j.gastro.2026.03.027

Chronic pancreatitis is a progressive fibroinflammatory disease of the pancreas that causes recurrent or chronic abdominal pain and functional insufficiency. Chronic pancreatitis follows the conceptual model of acinar cell injury, which lea…

2026
Urine Proteomics Identifies Biomarkers for Diagnosis and Fibrosis Severity in Pediatric Chronic Pancreatitis.
Clinical and translational gastroenterology ·doi:10.14309/ctg.0000000000000981

IntroductionReliable biomarkers for the diagnosis of chronic pancreatitis (CP) and pancreatic fibrosis severity are lacking, hindering effective treatment and management. Histologic fibrosis is a hallmark of late-stage CP, but noninvasive m…

2024
Pancreatic quantitative sensory testing to predict treatment response of endoscopic therapy or surgery for painful chronic pancreatitis with pancreatic duct obstruction: study protocol for an observational clinical trial.
BMJ open ·doi:10.1136/bmjopen-2023-081505

IntroductionTreatment for abdominal pain in patients with chronic pancreatitis (CP) remains challenging in the setting of central nervous system sensitisation, a phenomenon of remodelling and neuronal hyperexcitability resulting from persis…

2022
Rationale and Design for the Diabetes RElated to Acute Pancreatitis and Its Mechanisms Study: A Prospective Cohort Study From the Type 1 Diabetes in Acute Pancreatitis Consortium.
Pancreas ·doi:10.1097/mpa.0000000000002079

AbstractAcute pancreatitis (AP) is a disease characterized by an acute inflammatory phase followed by a convalescent phase. Diabetes mellitus (DM) was historically felt to be a transient phenomenon related to acute inflammation; however, it…