Yadav D

Introduction and importanceOvarian ectopic pregnancy (OEP) is a rare but serious condition, accounting for only 0.5-3% of all ectopic pregnancies. Because it is so uncommon and its symptoms often mimic other conditions, diagnosing OEP can b…

IntroductionHeavy menstrual bleeding (HMB) is a prevalent gynecological condition among women in the reproductive and perimenopausal age groups, significantly impairing quality of life. While several medical treatment options are available,…

Recurrent acute and chronic pancreatitis (RAP, CP) are complex, progressive inflammatory diseases with variable pain experiences impacting patient function and quality of life. The genetic variants and pain pathways in patients contributing…

BackgroundThe impact of multiple substance use on the risk of pancreatitis remains underexplored.ObjectiveTo systematically review peer-reviewed observational studies assessing the association of multiple substance use with the risk of acut…

IntroductionGastrointestinal hospitalisations in the USA cause over US$130 billion in expenditures, and acute pancreatitis is a leading cause of these hospitalisations. Adequate pain control is one of the primary treatment goals for acute p…

Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS) is a rare congenital disorder characterized by agenesis of the uterus and upper two-thirds of the vagina. It affects around 1 in 4000-5000 females and is of two types: type 1, also known as is…

IntroductionTreatment for abdominal pain in patients with chronic pancreatitis (CP) remains challenging in the setting of central nervous system sensitisation, a phenomenon of remodelling and neuronal hyperexcitability resulting from persis…

IntroductionChronic pancreatitis (CP) is a progressive fibroinflammatory disorder lacking therapies and biomarkers. Neutrophil gelatinase-associated lipocalin (NGAL) is a proinflammatory cytokine elevated during inflammation that binds fatt…

Background and aimsPain is the primary symptom of chronic pancreatitis (CP) and has been associated with abnormal pain processing and psychologic distress. Little is known about these phenomena in patients with painless disease. The aim of …

AbstractAcute pancreatitis (AP) is a disease characterized by an acute inflammatory phase followed by a convalescent phase. Diabetes mellitus (DM) was historically felt to be a transient phenomenon related to acute inflammation; however, it…

ImportanceChronic pancreatitis (CP) is a chronic inflammatory and fibrotic disease of the pancreas with a prevalence of 42 to 73 per 100 000 adults in the United States.ObservationsBoth genetic and environmental factors are thought to contr…

CASE REPORT A 58-year-old woman with a history of chronic diarrhea and post-menopausal uterine bleeding underwent a routine colonoscopy for colon cancer screening, which demonstrated a large, nearly obstructing mass extending from the proxi…

Background/objectivesOur aim was to validate recent epidemiologic trends and describe the distribution of TIGAR-O risk factors in chronic pancreatitis (CP) patients.MethodsThe NAPS-2 Continuation and Validation (NAPS2-CV) study prospectivel…

BackgroundA definition of chronic pancreatitis (CP) is needed for diagnosis and distinguishing CP from other disorders. Previous definitions focused on morphology. Advances in epidemiology, genetics, molecular biology, modeling and other di…

Background & aimsEndoscopic therapy (ET) frequently is used to treat patients with painful chronic pancreatitis (CP), but little is known about outcomes of patients for whom ET was not successful who then underwent surgery, or outcomes afte…