Morris DW — Endo Lab

2013

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.

Nature genetics ·doi:10.1038/ng.2711

Most psychiatric disorders are moderately to highly heritable. The degree to which genetic variation is unique to individual disorders or shared across disorders is unclear. To examine shared genetic etiology, we use genome-wide genotype da…

rct 2000

Depressive mood symptoms associated with ovarian suppression

Fertility and sterility ·doi:10.1016/s0015-0282(00)01607-1

OBJECTIVE: To determine if sertraline is helpful in the management of depressive symptoms associated with ovarian suppression during GnRH agonist therapy as compared with a placebo-controlled group. DESIGN: Double-blind placebo-controlled …

review 1998

Depressive symptoms associated with gonadotropin-releasing hormone agonists

Depression and anxiety ·doi:10.1002/(sici)1520-6394(1998)7:4<171::aid-da5>3.0.co;2-d

The gonadotropin-releasing hormone (GnRH) agonists are a relatively new class of drugs that are potentially effective in treating disorders that are aggravated either by estrogen or testosterone. GnRH agonists are effective in the treatment…

article 1998

Sertraline in the Treatment of Depression Associated with Gonadotropin-Releasing Hormone Agonist Therapy

Biological psychiatry ·doi:10.1016/s0006-3223(97)00396-x

BackgroundEndometriosis is thought to affect 5-10% of reproductive age women in the general population and is commonly treated with gonadotropin-releasing hormone (GnRH) agonists. Recent studies suggest depressive symptoms are associated wi…