Luigi Devoto

No ORCID on file · 17 papers in corpus · active 1981-2017

Study types

  • article 15
  • review 2

Condition tags

  • endometriosis 12
  • infertility 1
article 2017
hCG activates Epac-Erk1/2 signaling regulating Progesterone Receptor expression and function in human endometrial stromal cells
·doi:10.1093/molehr/gax015

STUDY QUESTION: How does hCG signal in human endometrial stromal cells (ESCs) and what is its role in regulating ESC function? SUMMARY ANSWER: hCG signaling in ESCs activates the extracellular signal-regulated protein kinases 1 and 2 (Erk1/…

article 2017
In-vitro study of gonadotrophin signaling pathways in human granulosa cells in relation to progesterone receptor expression
·doi:10.1016/j.rbmo.2017.06.011

In humans, data on gonadotrophin-activated (LH, HCG and FSH) progesterone receptor expression and signalling pathways involved in matrix metalloproteinases (MMPs) expression presumably linked to the follicle rupture, are limited. Our hypoth…

article 2017
The endometria of women with endometriosis exhibit dysfunctional expression of complement regulatory proteins during the mid secretory phase
Journal of reproductive immunology ·doi:10.1016/j.jri.2017.10.046

The control of complement activation within embryo-endometrium environment is critical for embryo survival. Cell evasion from complement attack requires interaction of complement regulatory proteins (CRPs) with cell adhesion αvβ3 integrin. …

article 2016
Endometrial expression and in vitro modulation of the iron transporter divalent metal transporter-1: implications for endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2016.04.002

ObjectiveTo evaluate divalent metal transporter-1 (DMT1) expression in healthy women's and endometriosis patients' endometrium and to analyze DMT1 and ferritin light chain (Fn-L) expression modulation by iron overload and IL-1β in endometri…

article 2016
The endometrial expression and paracrine regulation of complement regulatory protein decay accelerating factor in response to embryo signal human chorionic gonadotropin is impaired in endometria from women with endometriosis
·doi:10.1016/j.fertnstert.2016.07.789
article 2015
Eutopic endometrium from women with endometriosis exhibits decreased levels of complement decay- accelerating factor and abnormal expression of progesterone receptor during the implantation window
·doi:10.1016/j.placenta.2015.01.430
article 2014
Iron overload–modulated nuclear factor kappa-B activation in human endometrial stromal cells as a mechanism postulated in endometriosis pathogenesis
Fertility and sterility ·doi:10.1016/j.fertnstert.2014.10.046

ObjectiveTo evaluate the effect of iron overload on nuclear factor kappa-B (NF-κB) activation in human endometrial stromal cells (ESCs).DesignExperimental study.SettingUniversity hospital research laboratory.Patient(s)Ten healthy women.Inte…

article 2013
Endometriosis, endometrium, implantation and fallopian tube
·doi:10.1093/humrep/det211

Study question: To compare the pregnancy rate in patients submitted to FET (Frozen Embryos Transfer) of cleavage stage embryos (Group 1), or at the blastocyst stage (Group 2). Summary answer: Our data showed that the transfer of frozen blas…

review 2012
Nuclear factor-kappaB: a main regulator of inflammation and cell survival in endometriosis pathophysiology
Fertility and sterility ·doi:10.1016/j.fertnstert.2012.06.021

OBJECTIVE: To update, analyze, and summarize the literature concerning nuclear factor-kappaB (NF-κB) participation in endometriosis pathophysiology. DESIGN: Review. RESULT(S): Nuclear factor-kappaB is physiologically activated in the huma…

article 2012
SESSION 34: ENDOMETRIOSIS/ENDOMETRIUM: MOLECULAR AND CELLULAR INSIGHTS 1
·doi:10.1093/humrep/27.s2.33
article 2011
Physiologic activation of nuclear factor kappa-B in the endometrium during the menstrual cycle is altered in endometriosis patients
Fertility and sterility ·doi:10.1016/j.fertnstert.2011.12.006

ObjectiveTo evaluate nuclear factor kappaB (NF-κB) activation and NF-κB-p65 subunit activation, immunolocalization, and expression in the endometrium of healthy women and endometriosis patients throughout the menstrual cycle.DesignProspecti…

article 2011
POSTER VIEWING SESSION - ENDOMETRIOSIS, ENDOMETRIUM, IMPLANTATION AND FALLOPIAN TUBE
·doi:10.1093/humrep/26.s1.80
review 2010
Involvement of the nuclear factor-κB pathway in the pathogenesis of endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2010.01.013

ObjectiveTo evaluate the role of nuclear factor-κB (NF-κB) in the pathogenesis of endometriosis.DesignA literature search was conducted in PubMed to identify all relevant citations.Result(s)Our findings highlight the important role of NF-κB…

article 2010
Posters * Endometriosis, Endometrium and Implantation
·doi:10.1093/humrep/de.25.s1.242

Introduction: Endometriosis, defined as the growth of endometrial tissue outside \nthe uterine cavity is a common gynaecological disorder affecting 10-15% \nof women in their reproductive years. It is a major clinical problem causing in- \n…

article 2009
Surgical Managment of the Non-Communicating Uterine Horn
·doi:10.1016/j.jmig.2009.08.031
article 1984
Estradiol and progesterone nuclear and cytosol receptors of hydrosalpinx
·doi:10.1016/s0015-0282(16)48144-6

Hydrosalpinx is usually associated with a low intrauterine pregnancy rate following restoration of tubal patency by microsurgery. The biochemical evaluation of pathologic tubes from 11 infertile patients showed the presence of estradiol (E2…

article 1981
Estradiol dehydrogenase activity in the fallopian tube during the normal menstrual cycle
·doi:10.1007/bf02111802

Simultaneous determinations of 17 beta-estradiol dehydrogenase activity (17 beta-HSDH) and of estradiol (E2), estrone (E1), and progesterone (P) were made in homogenates of human tubal tissue. The oviducts were obtained from 16 multi-parous…