Xiao-Yong Zhu

No ORCID on file · 15 papers in corpus · active 2006-2023

Study types

  • article 11
  • other 4

Condition tags

  • endometriosis 14
  • mesh:D004715 13
  • endometrioma 1
other 2023
Biochimica et biophysica acta. Molecular basis of disease ·doi:10.1016/j.bbadis.2023.166761

Endometriosis is an estrogen-dependent, progesterone-resistant gynecological disease with an unknown pathogenesis. Compared to women without endometriosis, women with endometriosis have a remarkably high heme level in the peritoneal fluid. …

article 2019
Reproduction (Cambridge, England) ·doi:10.1530/rep-19-0028

Endometriosis (EMS) is a chronic inflammatory disease characterized by the presence of extrauterine endometrial tissues. It has been previously reported that the refluxed blood containing viable endometrial tissues and the defective elimina…

other 2019
International journal of molecular medicine ·doi:10.3892/ijmm.2018.4021

Angiogenesis is an essential process involved in various physiological, including placentation, and pathological, including cancer and endometriosis, processes. Melatonin (MLT), a well‑known natural hormone secreted primarily in the pineal …

other 2018
Autophagy ·doi:10.1080/15548627.2018.1476809

UNLABELLED: Impaired NK cell cytotoxic activity contributes to the local dysfunctional immune environment in endometriosis (EMS), which is an estrogen-dependent gynecological disease that affects the function of ectopic endometrial tissue c…

article 2017
Cell death & disease ·doi:10.1038/cddis.2017.95

Abstract Endometriosis is an estrogen-dependent inflammatory disease. The anti-inflammatory cytokine IL-10 is also increased in endometriosis. IL-10 production by Th17 cells is critical for limiting autoimmunity and inflammatory responses. …

article 2016
Reproduction (Cambridge, England) ·doi:10.1530/rep-16-0278

Macrophages play an important role in the origin and development of endometriosis. Estrogen promoted the growth of decidual stromal cells (DSCs) by downregulating the level of interleukin (IL)-24. The aim of this study was to clarify the ro…

article 2015
Human Reproduction ·doi:10.1093/humrep/dev100

STUDY QUESTION: What mechanism is involved in regulating the autophagy of endometrial stromal cells (ESCs), and does it participate in the pathogenesis of endometriosis? SUMMARY ANSWER: CXCL12 down-regulates secretory phase ESC autophagy. W…

article 2014
International journal of clinical and experimental pathology

In the peritoneal fluid, macrophages and their secretory cytokines are essential for endometriosis, but the factors that favor their involvement in the endometriosis-associated inflammatory response are still elusive. Given the anomalous ex…

article 2013
International journal of clinical and experimental pathology

Evidence for an immunosuppressive function of indoleamine 2,3-dioxygenase (IDO) has been accumulating. However, the unusual distribution of IDO1 in gynecologic cancer cells suggests that modulating immunity may not its only function. To cla…

article 2013
Human Reproduction ·doi:10.1093/humrep/det248

STUDY QUESTION: Is Nometastatic gene 23-H1 (NME1, also known as nm23-H1) involved in regulating the biological behavior of endometrial stromal cells (ESCs), and does it participate in the pathogenesis of endometriosis? SUMMARY ANSWER: NME1 …

article 2012
Fertility and sterility ·doi:10.1016/j.fertnstert.2011.12.049
article 2012
Human Reproduction ·doi:10.1093/humrep/des132

BACKGROUND: Chemokine CXCL8 (also known as IL-8) has been identified as a potential regulator of endometrial stromal cells (ESCs), but it is unclear how CXCL8 regulates the survival of ESCs in the pathogenesis of endometriosis. METHODS: We …

other 2012
Molecular human reproduction ·doi:10.1093/molehr/gas021

Indoleamine 2,3-dioxygenase-1 (IDO1) is an intracellular enzyme that catalyses essential amino acid tryptophan along the kynurenine pathway. The aim of this study was to determine the impact of IDO1 expression on the biological characterist…

article 2007
Fertility and sterility ·doi:10.1016/j.fertnstert.2006.11.129
article 2006
Human Reproduction ·doi:10.1093/humrep/dei414

BACKGROUND: Chemokines play an important role in the pathogenesis of endometriosis. In the present study, the transcription of 18 chemokine receptors in eutopic endometrium and ectopic tissue with endometriosis was first analysed by RT-PCR.…