Gaskins AJ

OBJECTIVE: Disordered eating behaviors may impact the gynecologic health of adolescents through effects on menstrual cycle function and body size; however, few studies have evaluated these associations. This study aimed to prospectively inv…

BackgroundWhile extreme ambient heat has been associated with several adverse pregnancy and birth outcomes little is known regarding the link between extreme ambient temperatures and human fertility.ObjectiveTo evaluate the associations bet…

INTRODUCTION: There is increasing evidence that women who have experienced infertility are at greater risk for several chronic conditions. However, the mechanisms underlying these associations are not clear. Pathophysiology may be illuminat…

Many endocrine-disrupting chemicals have been linked to impaired ovarian function and fertility. However, most research has focused on small numbers of known chemicals in blood or urine. We aimed to measure the untargeted chemical exposome …

OBJECTIVE: To prospectively assess the effect of endometriosis and uterine fibroids on the long term risk of premature mortality (younger than 70 years). DESIGN: Prospective cohort study SETTING: The Nurses' Health Study II, United States …

OBJECTIVES: To better understand whether history of infertility is associated with anti-Müllerian hormone (AMH) levels later in life, outside of reproduction. METHODS: Among 1,758 premenopausal women in the Nurses' Health Study II with mea…

BackgroundThere is evidence that in-utero exposure to PBBs, and similar chemicals, are associated with several adverse reproductive health outcomes including altered pubertal timing. However, less is known about the effects of in-utero expo…

ObjectiveTo investigate the association between infertility and the incidence of invasive cancer.DesignProspective cohort study (1989-2015).SettingNot applicable.Patient(s)A total of 103,080 women aged 25-42 years in the Nurses' Health Stud…

BACKGROUND: Women are at greater risk than men of developing chronic inflammatory conditions and "long COVID." However, few gynecologic health risk factors for long COVID-19 have been identified. Endometriosis is a common gynecologic disord…

Identifying genetic determinants of reproductive success may highlight mechanisms underlying fertility and identify alleles under present-day selection. Using data in 785,604 individuals of European ancestry, we identified 43 genomic loci a…

PurposeResearch on infertility and risk of breast cancer has been conflicting, potentially because many well-established breast cancer risk factors, such as pregnancy history, are strongly correlated with infertility.MethodsWe followed part…

OBJECTIVE: We conducted a systematic review and meta-analysis of the effects of Mediterranean diet on female reproductive health outcomes over the life-course. DATA SOURCES: We searched PubMed, Embase, MEDLINE, Cochrane Central Register of…

BackgroundAs the use of in vitro fertilization continues to increase in the United States, up-to-date models that estimate cumulative live birth rates after multiple oocyte retrievals and embryo transfers (fresh and frozen) are valuable for…

BackgroundDespite anecdotal reports, the impacts of SARS-CoV-2 infection or COVID-19 vaccination on menstrual health have not been systemically investigated.ObjectiveThis study aimed to examine the associations of SARS-CoV-2 infection and C…

BACKGROUND: Infertility has been associated with common chronic non-communicable diseases. However, the association of infertility with long-term mortality is unclear. METHODS: We followed 101,777 women aged 25-42 years at enrollment betwe…

ObjectiveTo compare the variability in metabolomes between the serum and follicular fluid, as well as across 3 dominant follicles.DesignProspective cohort study.SettingAn academic fertility clinic in the northeastern United States, 2005-201…

ObjectiveTo examine the association between dietary folate intake and antral follicle count (AFC) among women seeing treatment for infertility.DesignCohort study.SettingAcademic fertility center.PatientsA total of 552 women attending the Ma…

ObjectiveTo examine the association between ambient temperature and antral follicle count (AFC), a standard measure of ovarian reserve.DesignProspective cohort study.SettingFertility center at an academic hospital in the northeastern United…

BackgroundFew epidemiologic studies have evaluated the impact of paternal environmental exposures, particularly as mixtures, on couples' pregnancy outcomes.ObjectiveWe investigated whether mixtures of paternal urinary bisphenol A (BPA), par…

BackgroundOverweight and obesity among women have been associated with lower success of assisted reproduction technologies (ARTs). However, the relation of adolescent body weight and adult weight change to ART outcomes is not well understoo…

BackgroundNatural vegetation, or greenness, is thought to improve health through its ability to buffer and reduce harmful environmental exposures as well as relieve stress, promote physical activity, restore attention, and increase social c…

PurposeOocyte donor in vitro fertilization (IVF) represents an ideal model to study the effects of embryo stage on reproductive success, as embryos come from young women with high-quality oocytes. Our study aimed to determine if embryo tran…

Accumulating evidence suggests that air pollution increases pregnancy loss; however, most previous studies have focused on case identification from medical records, which may underrepresent early pregnancy losses. Our objective was to inves…

ObjectiveTo investigate the associations between dietary patterns and antral follicle count (AFC), a marker of ovarian reserve.DesignProspective cohort study.SettingFertility center at an academic hospital.Patient(s)A total of 363 women see…

OBJECTIVE: To investigate the relationship between endometriosis and adverse pregnancy outcomes. METHODS: Women between ages 25 and 42 years in 1989 (n=116,429) reported detailed information on pregnancies and reproductive health at baselin…