Yingli Shi

Endometriosis is a common gynecological disease and the pathogenesis is not clearly understood. Previous studies have demonstrated via microarray techniques that microRNA (miR)‑449b was significantly downregulated both in ectopic and eutopi…

We applied in the previous study miRNA microarray screening analysis to identify several differentially expressed miRNAs, including miR-183 in normal, eutopic, and ectopic endometrium. Knockdown of miR-183 expression induced the invasivenes…

Endometriosis is a common gynecological disease, yet its pathogenesis remains poorly understood. Recent studies have demonstrated that the aberrant expression of certain microRNAs (miRNAs) may correlate with the development and progression …

Endometriosis is a common disease in females of reproductive age and has the classic characteristic of mononuclear cell infiltration into lesions. Shikonin is an anti‑inflammatory phytocompound obtained from Lithospermum erythrorhizon whose…

Objective To evaluate the expression levels of chemokine receptor 6 (CCR6) in the eutopic endometrium and ectopic endometrium of patients with endometriosis,and to study the pathogenesis of endometriosis. Methods Immunohistochemistry was us…

RANTES (C-C chemokine, regulated on activation, normal T cell expressed and secreted) is involved in progression of endometriosis, but the precise mechanism is understood inadequately. This study is to elucidate the roles of RANTES in macro…

ObjectiveTo explore the effects of the combined E(2) with the environmental pollutant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on CCR8-I-309 expression by the endometriotic lesion-associated cells in the pathogenesis of endometriosis.Desi…

To explore modulatory effect of the combined effect of estradiol and TCDD on IL-8 expression and auto-endocrine role in endometrial stromal cells(ESC).Immunohistochemistry was used to evaluate the protein translation of CXCR1 in eutopic end…

BACKGROUND: Chemokines play an important role in the pathogenesis of endometriosis. In the present study, the transcription of 18 chemokine receptors in eutopic endometrium and ectopic tissue with endometriosis was first analysed by RT-PCR.…

To elucidate the role of estradiol in the pathogenesis and development of endometriosis by exploring the effects of 17#beta#-estradiol on IL-8,MIP-1#alpha#, RANTES and I-309 secretion by endometrial stromal cells. IL-8,MIP-1#alpha#,RANTES a…

OBJECTIVE: To study the impact of bcl-2 and p53 protein expressions on the malignant transformation of ovarian endometriosis. METHODS: Immunohistochemical technique was used to detect the bcl-2 and p53 protein expressions in: endometriosis …