Sebastian-Leon P

No ORCID on file · 4 papers in corpus · active 2021-2026

Study types

  • other 1
  • preprint 1

Condition tags

  • endometriosis 2
  • infertility 2
other 2026
Descriptive overview of gene variants potentially affecting female infertility treatments: A systematic review
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie ·doi:10.1016/j.biopha.2025.118942

Pharmacogenetics is an emerging discipline that explores how genetic variants affect drug response, potentially leading to side effects or treatment failure. Although widely applied in other medical specialties, its use in female reproducti…

2026
Endometrial cortisol level and its relationship with psychological stress, molecular tissue changes, and clinical outcomes in infertile women.
Scientific reports ·doi:10.1038/s41598-026-41233-8

Despite fertility treatments are a stressful journey, there remains a lack of studies assessing how stress is affecting endometrial function in infertility. This prospective cohort study, including 84 endometrial biopsies, aims to elucidate…

preprint 2025
Systems Pharmacology Model Predicts Zinc and Copper Can Be Repurposed as Endometriosis Therapies
·doi:10.1101/2025.10.06.25337149

Abstract BACKGROUND Endometriosis is a complex and polygenic disease characterized by the growth of endometrial-like tissue outside the uterus. Associated conditions include pelvic pain and infertility among others. Current treatments of en…

2021
P–294 Mapping COVID–19 affected genes from blood in a Window of implantation co-expression network reveals a potentially compromised landscape
Human reproduction (Oxford, England)

Abstract Study question Could the transcriptomic and functional landscape of the window of implantation be compromised by SARS-COV–2 infection? Summary answer Some of the main genes and pathways involved in the window of implantation are af…