STUDY QUESTION: Do DNA variants in the growth regulation by estrogen in breast cancer 1 (GREB1) region regulate endometrial GREB1 expression and increase the risk of developing endometriosis in women?
Medical therapy for patients with endometriosis often fails or produces substantial adverse effects including a contraceptive effect in women wishing to conceive. Surgery is a major treatment option for such patients. Surgical choices inclu…
BACKGROUND: Surgical treatment of deep infiltrating endometriosis (DIE) is complex, and preoperative diagnosis benefits both surgeon and patient. Studies in expert centres have reported high accuracy for transvaginal ultrasound (TVUS) diagn…
STUDY OBJECTIVE: To compare reduction of pain after laparoscopy for ablation or excision of endometriosis. DESIGN: Prospective, randomized, double-blind study (Canadian Task Force classification I). SETTING: Endometriosis and pelvic pain …
Purpose The purpose of this study was to develop a test to discriminate between women suffering from pelvic pain associated with presence or absence of endometriosis, using symptom visual analogue scale (VAS) scores, demographic and lifesty…
INTRODUCTION AND HYPOTHESIS: The purpose is to demonstrate a surgical case of severe endometriosis involving a bladder endometriotic nodule. METHODS: This patient has a large 4-cm endometriotic nodule which obliterates the uterovesical pou…
INTRODUCTION AND HYPOTHESIS: This study assesses the prevalence of interstitial cystitis (IC)/bladder pain syndrome (BPS) in women with chronic pelvic pain (CPP). METHODS: This was a prospective study of 150 women undergoing laparoscopy as…
Surgical treatment of DIE is complex and preoperative diagnosis benefits both surgeon and patient. Several studies have reported high accuracy for the TVUS diagnosis of DIE, however, these studies were performed by experts who developed the…
OBJECTIVE: To compare reduction of pain following laparoscopy after ablation or excision of endometriosis. DESIGN: A prospective, randomized, double-blind study. SETTING: Endometriosis and pelvic pain clinic at a university teaching hospi…
To date, the quest to develop a noninvasive diagnostic test for endometriosis has mostly concentrated on the levels of cytokines and growth factors that are involved in inflammation, angioneogenesis and tissue remodeling, present in serum, …
STUDY OBJECTIVE: To assess the outcome of aggressive but conservative laparoscopic surgery in the treatment of severe endometriosis involving the rectum. DESIGN: Retrospective study (Canadian Task Force classification III). SETTING: Endos…
Current literature describes 3 different pathogenetic types of ovarian endometriotic cysts. Cortical invagination cysts arise when surface ovarian endometriotic deposits adhere to another structure (such as the broad ligament), blocking the…
Objective To highlight the necessity of adequately testing rectosigmoid integrity after resection of infiltrating endometriosis. Subject A 25‐year‐old woman with a past history of ablative treatment for endometriosis, symptoms suggestive of…
An open prospective observational study was performed, aiming to measure symptom severity following operative gynaecological laparoscopy and explore any associated factors. Women having concomitant procedures were excluded. Each woman had s…