ObjectiveAlthough ovarian clear cell adenocarcinoma (OCCA) and ovarian endometrioid adenocarcinoma (EC) are considered to be closely related to endometriosis, the mechanisms of carcinogenesis of these two malignancies and malignant transfor…
OBJECTIVE: To determine the effects of oxidative stress on the quality of oocytes and embryos, 8-hydroxy-2'-deoxyguanosine (8-OHdG) in granulosa cells was quantitatively studied during an in vitro fertilization and embryo transfer (IVF-ET) …
Endometriosis is associated with marked subfertility and various causes for this subfertility have been previously studied. The poor quality of oocytes has been suggested as one possible cause. In this study, we evaluated the quality of ooc…
A 52-year-old woman suffered from acute massive myocardial infarction in association with a large thrombus in the ascending aorta. She was a moderate smoker and was taking hormone supplement therapy for menopausal hormone insufficiency and …
OBJECTIVE: Steroid sulfatase (STS) is an important enzyme that converts biological inactive steroid sulfate to active free steroid. As estrogen is thought to play an important role in cell proliferation in gynecological cancer, the existenc…
PurposeThe objective was to determine the effects of women's age on the ovarian fecundity as assessed by the incidence of apoptotic granulosa cells.MethodsTwenty-eight normo-ovulatory women underwent ovulation induction for standard IVF. Th…
PurposeThe aim was to investigate which ovarian hyperstimulation protocol performed in the same patients causes development of oocytes of good quality.MethodsTwenty normo-ovulatory women underwent three different controlled ovarian hypersti…
PurposeThis study was designed to examine whether hyaluronic acid (HA) inhibits apoptosis in cumulus and mural granulosa cells and to examine whether this effect of HA was mediated through CD44.MethodsMural and cumulus granulosa cells were …
ObjectiveTo determine whether folliculogenesis is impaired in patients with endometriosis.DesignProspective study.SettingYamagata University School of Medicine, Yamagata, Japan.Patient(s)Thirty women participating in an IVF program.Interven…
CD44 is a polymorphic and polyfunctional transmembrane glycoprotein widely expressed in many types of cells. Here, the expression of this protein on human membrana granulosa was studied by two techniques. Using confocal laser scanning micro…
OBJECTIVE: To investigate the incidence of apoptotic bodies in membrana granulosa in patients with endometriosis. DESIGN: Retrospective analysis. SETTING: Yamagata University Hospital. PATIENT(S): Fifty-eight normoovulatory women with en…
Three cases of catamenial pneumothorax were presented. A 42-year-old woman with intrapelvic endometriosis had recurrent right-sided pneumothorax with menstruation more than six times. At the operation only a bleb was noted at the apex of th…