Zhang J

Analgesia by non-steroidal anti-inflammatory drugs (NSAIDs) is ascribed to inhibition of prostaglandin (PG) biosynthesis and ensuing inflammation. However, NSAIDs have life-threatening side effects, and inhibition of inflammation delays pai…

Endometriosis affects a substantial number of women of reproductive age, yet current diagnostic methods rely on invasive procedures. To address this limitation, we investigated THBS1 as a potential biomarker and regulator of disease progres…

Background: Ovarian clear cell carcinoma (OCCC) is characterized by chemoresistance and poor prognosis in advanced or recurrent cases. This study aimed to find specific prognostic markers for OCCC. Methods: We analyzed 169 OCCC patients for…

The present study aimed to explore whether there is an association between the transfer of frozen thawed embryos (FET) obtained during SARS-CoV-2 infection and an increased risk of adverse pregnancy outcomes. We performed a case-control coh…

Background: Sleep disorder in women of reproductive age may contribute to infertility development, but there is a lack of substantial evidence linking sleep disorder to inflammation and oxidative stress, and the subsequent risk of infertili…

Abstract Background :To analyze the prevalence and burden of disease (Disability-Adjusted Life Years) of endometriosis in 204 countries and regions from 1990 to 2021, and evaluate its global trends, regional differences and association …

BackgroundFemale reproductive disorders (FRDs) are common diseases among women of childbearing age, affecting their reproductive health. Age at first sexual intercourse (AFS) is potentially linked to FRDs, and this study aims to investigate…

ObjectiveTo analyze the expression levels of the oocyte-secreted factors growth differentiation factor-9 (GDF-9) and bone morphogenetic protein-15 (BMP-15) in cumulus cells (CCs) under different controlled ovarian stimulation (COS) protocol…

Pyroptosis is a novel form of programmed cell death that depends on gasdermin-mediated pore formation in the plasma membrane and the release of inflammatory factors. Pyroptosis is closely linked to the occurrence and progression of almost a…

ObjectiveTricho-rhino-phalangeal syndrome-1 (TRPS1), an atypical GATA transcription factor, plays a critical role in diverse physiological and pathological processes and holds potential as a biomarker for diseases and targeted tumor therapi…

ObjectiveTo analyze the value of serum human chorionic gonadotropin (β-HCG), anti-Mullerian hormone (AMH), progesterone (P)/ estradiol (E2) in predicting the pregnancy outcome of frozen-thawed embryo transfer (FET) cycle in patients with lo…

BackgroundCholangiocarcinoma is a common hepatic malignant tumor with an unfavorable prognosis. Therefore, we systematically evaluated the transcriptomic landscape of CHOL by whole transcriptome sequencing technology in this study and const…

Synopsis PET/CT can differentiate between endometriosis, the malignant progression of endometriosis, and ovarian cysts.

BACKGROUND: Endometriosis involves the intestine, and its clinical manifestations are nonspecific and lack of etiological manifestations. The diagnosis is difficult, which often leads to misdiagnosis. We report a case of endometriosis which…

Yufei Liang,1 Lina Mei,2 Qipeng Ning,2 Jiao Zhang,2 Jingying Fei,3 Jie Dong1 1Department of Gynaecology and Obstetrics, Huzhou Maternity & Child Health Care Hospital, Huzhou, People’s Republic of China; 2Department of Digestive, Huzhou Mate…

Oxidative stress dysfunction has recently been found to be involved in the pathogenesis of premature ovarian insufficiency (POI). Previously, we found that advanced oxidation protein products (AOPPs) in plasma were elevated in women with PO…

OBJECTIVE: To analyze the factors that might influence the pregnancy rate in patients with infertility related to endometriosis (EMs) after undergoing laparoscopic surgery, providing guidance for our clinical diagnostic and therapeutic deci…

ObjectiveThe objective of this study was to investigate the correlation between various factors and the clinical outcomes of Intrauterine Insemination (IUI) in both young and aged patients, aiming to provide a theoretical basis for clinical…

ObjectiveThe objective was to analyze the impact of the uterine artery pulsatility index (PI) on pregnancy outcomes by measuring uterine artery blood flow on the day of endometrial transformation in patients undergoing frozen-thawed embryo …

BackgroundCancer-derived exosomes contribute significantly in intracellular communication, particularly during tumorigenesis. Here, we aimed to identify two immune-related ovarian cancer-derived exosomes (IOCEs) subgroups in ovarian cancer …

PurposeTo evaluate whether co-treatment of repeated GnRHa triggers with GnRH antagonist protocols can improve the clinical outcomes in in vitro fertilization/intracytoplasmic sperm injection and embryo transfer (IVF/ICSI-ET) procedures.Meth…

PURPOSE: To investigate the association between the oxidative balance score (OBS) and endometriosis. METHODS: This cross-sectional study used four cycles of the National Health and Nutrition Examination Survey (NHANES) (1999-2000, 2001-200…

Xiaoming Zhou,1 Weiwei Shen,1 Jue Zhu,2 Yichen Chen,2 Jing Zhang2 1Department of Gynecology, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, 315010, People’s Republic of China; 2Department of Gynecology, Ningbo Women &…

Abstract Background: Living habits affect women's endocrine and fertility over time with aging and in certain circumstances, according to which we can promote women's reproductive health by adjusting living habits. Methods: We utilized two…

Abstract Background: The C-reactive protein-triglyceride glucose index (CTI), a promising new marker, could evaluate the extent of inflammation. Endometriosis is a prevalent chronic inflammatory condition that is influenced by estrogen and…