H Sunny Sun

No ORCID on file · 9 papers in corpus
2019
EBioMedicine ·doi:10.1016/j.ebiom.2019.02.059

BackgroundHypoxia suppresses global protein production, yet certain essential proteins are translated through alternative pathways to survive under hypoxic stress. Translation via the internal ribosome entry site (IRES) is a means to produc…

article 2015
Molecular human reproduction ·doi:10.1093/molehr/gav054

STUDY HYPOTHESIS: DNA methylation is regulated by hypoxia in endometriosis. STUDY FINDING: Hypoxia causes global hypomethylation through AU-rich element binding factor 1 (AUF1)/microRNA-148a (miR-148a)-mediated destabilization of DNA methyl…

2014
Nucleic acids research ·doi:10.1093/nar/gkt1286

Human fibroblast growth factor 9 (FGF9) is a potent mitogen involved in many physiological processes. Although FGF9 messenger RNA (mRNA) is ubiquitously expressed in embryos, FGF9 protein expression is generally low and restricted to a few …

2011
Nucleic acids research ·doi:10.1093/nar/gkq1295

A TG microsatellite in the 3'-untranslated region (UTR) of FGF9 mRNA has previously been shown to modulate FGF9 expression. In the present study, we investigate the possible interacting protein that binds to FGF9 3'-UTR UG-repeat and study …

2010
Nucleic acids research ·doi:10.1093/nar/gkq717

Fibroblast growth factor 9 (FGF9) is an autocrine/paracrine growth factor that plays vital roles in many physiologic processes including embryonic development. Aberrant expression of FGF9 causes human diseases and thus it highlights the imp…

article 2006
Molecular and cellular biology ·doi:10.1128/mcb.00941-06

Fibroblast growth factor 9 (FGF-9) is a potent mitogen that controls the proper development of many tissues and organs. In contrast, aberrant expression of FGF-9 also results in the evolution of many human diseases, such as cancers and endo…

article 2003
Endocrinology ·doi:10.1210/en.2003-0289

Steroidogenic acute regulatory protein (StAR) regulates the first committed step in the biosynthesis of steroids, and thus aberrant expression of StAR in endometriotic implants plays a critical role in the etiology of endometriosis. However…

article 2002
Molecular human reproduction ·doi:10.1093/molehr/8.12.1103

Prostaglandin (PG) E2 has been shown to stimulate steroidogenesis in ectopic endometriotic stromal cells and may be involved in the development of endometriosis since this disorder is highly estrogen dependent. The biosynthesis of PGE2 is c…

article 2001
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.86.12.8082

The regulation of steroidogenic acute regulatory protein (StAR) gene expression and the synthesis of steroids from cholesterol in ectopic endometriosis tissues were investigated. Peritoneal fluid and endometrial tissues were collected from …