Caudell, David

Figure S1. Schematic illustrating experimental design for mitochondrial respirometric analyses. Tissues were collected from four nonhuman primates (NHPs) with and four without endometriosis (n =â 8 total NHPs). These NHPs were part of the …

Figure S1. Schematic illustrating experimental design for mitochondrial respirometric analyses. Tissues were collected from four nonhuman primates (NHPs) with and four without endometriosis (n =â 8 total NHPs). These NHPs were part of the …

Figure S2. A representative OCR output graph from the Seahorse XF24–3 Extracellular Flux Analyzer (Agilent Technologies, Santa Clara, CA, USA). In this example, samples were run according to tissue type (endometrium, EM; or endometriosis, E…

Figure S2. A representative OCR output graph from the Seahorse XF24–3 Extracellular Flux Analyzer (Agilent Technologies, Santa Clara, CA, USA). In this example, samples were run according to tissue type (endometrium, EM; or endometriosis, E…

Figure S3. Targeted metabolomics experimental design and statistical analysis. Eight clinically healthy and 17 nonhuman primates (NHP) with endometriosis were identified through the Wake Forest Primate Center Comprehensive Animal Record Sys…

Figure S3. Targeted metabolomics experimental design and statistical analysis. Eight clinically healthy and 17 nonhuman primates (NHP) with endometriosis were identified through the Wake Forest Primate Center Comprehensive Animal Record Sys…

Figure S4. Complex II-mediated OCR remained significantly decreased after exclusion of the NHP with an atrophic endometrium. A) Endometrial mitochondrial OCR is decreased at baseline (EM, p = 0.02), B) energy state 3 (p = 0.03), and C) ener…

Figure S4. Complex II-mediated OCR remained significantly decreased after exclusion of the NHP with an atrophic endometrium. A) Endometrial mitochondrial OCR is decreased at baseline (EM, p = 0.02), B) energy state 3 (p = 0.03), and C) ener…

Table S1. M/z Transitions and Collision Energies (PDF 53 kb)

Table S1. M/z Transitions and Collision Energies (PDF 53 kb)

Abstract Background Endometriosis is the growth of uterine lining (endometrium) outside of the uterus. In other chronic inflammatory diseases, mitochondrial dysfunction is suspected of playing a role in disease pathogenesis. However, little…

Abstract Background Endometriosis is the growth of uterine lining (endometrium) outside of the uterus. In other chronic inflammatory diseases, mitochondrial dysfunction is suspected of playing a role in disease pathogenesis. However, little…