Additional file 1: of Endometrium and endometriosis tissue mitochondrial energy metabolism in a nonhuman primate model

Figure S1. Schematic illustrating experimental design for mitochondrial respirometric analyses. Tissues were collected from four nonhuman primates (NHPs) with and four without endometriosis (n =â 8 total NHPs). These NHPs were part of the larger metabolomics cohort. Endometrium and endometriosis tissue were collected from the four NHPs with endometriosis and were designated EM and EMO, respectively. Normal endometrium the clinically healthy NHPs was abbreviated nEM. Mitochondria were isolated from whole tissue and oxygen consumption rate (OCR) of electron transport chain (ETC) complex I- and complex II-mediated oxidative phosphorylation was assessed. OCR data for EM and EMO were compared to nEM using a one-way analysis of variance (ANOVA). Data from endometrium samples (EM and nEM) were combined and analyzed by ANOVA according to menstrual cycle phase. (DOCX 109 kb)