Kelton Tremellen

Polycystic ovary syndrome (PCOS) is a systemic metabolic and endocrine disorder that significantly disrupts reproductive physiology and endometrial function. In this narrative review, we examine the molecular impact of metabolic and hormona…

BACKGROUND: Currently, there is some evidence that adenomyosis patients using gonadotropin-releasing hormone (GnRH) agonist long downregulation (LDR) prior to embryo transfer may improve in vitro fertilization (IVF) success rate, but not to…

PurposeThe use of antioxidants is common practice in the management of infertile patients. However, there are no established guidelines by professional societies on antioxidant use for male infertility.Materials and methodsUsing an online s…

PurposeTo determine if the use of ICSI in women of advanced maternal age with non-male factor infertility increases chances of live birth.MethodsRetrospective data analysis of 10 years of cycle data from a single Australian IVF clinic (Repr…

Oxidative stress is prevalent among infertile men and is a significant cause of sperm DNA damage. Since sperm DNA damage may reduce embryo quality and increase miscarriage rates, it is possible that untreated sperm oxidative stress may impa…

[This corrects the article DOI: 10.1093/hropen/hoy011.].

STUDY QUESTION: Does the rate of miscarriage increase in the setting of adenomyosis independent of other known risk factors for miscarriage such as maternal age, BMI, embryo genetic status? SUMMARY ANSWER: Adenomyosis and high BMI both sign…

Department of Reproductive Medicine, Flinders University, Adelaide, South Australia, Australia Department of Reproductive Medicine, Repromed, Adelaide, South Australia, Australia Financial Disclosure The authors did not report any potential…

STUDY QUESTION: Does the presence of ultrasound diagnosed adenomyosis interfere with successful implantation in patients undergoing IVF treatment with GnRH antagonist ovarian stimulation? SUMMARY ANSWER: The presence of ultrasound diagnosed…

Four women, who previously had undergone multiple unsuccessful in vitro fertilisation (IVF) cycles because of failure of implantation of good quality embryos, were identified as having coexisting uterine adenomyosis. Endometrial biopsies sh…

Recurrent miscarriage affects approximately 1% of the population and in half of these cases no cause is found. Abnormally functioning immunocompetent cells, including natural killer (NK) cells, in the endometrium, are thought to be responsi…

Adenomyosis, a condition usually associated with multiparity, is not generally seen as a cause of infertility. However, recent studies have reported a reduction in IVF implantation rates and a link with miscarriage, suggesting that adenomyo…