Roger Hart

OBJECTIVES: The objectives of this study were to determine if radical laparoscopic excision of endometriosis (RLEE) improves long-term outcomes in the quality of life (QOL) and symptomatology experienced by women with the disease. Secondary…

BACKGROUND: Endometrioma are endometriotic deposits within the ovary. Laparoscopic management of endometriomas is associated with shorter hospital stay, faster recovery, and decreased hospital costs compared with laparotomy. The previous ve…

PurposeTo identify and characterise appropriate comparison groups for population studies of health outcomes in ART-conceived births: ovulation induction (OI), subfertile untreated and fertile natural conceptions. Our secondary objective was…

Editorial noteThis editorial note has been published online on March 5th, 2026, by the editors of the Cochrane Database of Systematic Reviews, in agreement with the authors, due to concerns discovered by Cochrane and the Managing Editor of …

BackgroundA frozen embryo transfer (FET) cycle is when one or more embryos (frozen during a previous treatment cycle) are thawed and transferred to the uterus. Some women undergo fresh embryo transfer (ET) cycles with embryos derived from d…

Study questionWhat is the recommended assessment and management of infertile women with polycystic ovary syndrome (PCOS), based on the best available evidence, clinical expertize and consumer preference?Summary answerInternational evidence-…

In vitro maturation (IVM) of human oocytes is an emerging treatment option for women with polycystic ovary/polycystic ovary syndrome (PCO/PCOS) in addition to the standard in vitro fertilization (IVF) treatment. There has been significant i…

BackgroundA couple may be considered to have fertility problems if they have been trying to conceive for over a year with no success. This may affect up to a quarter of all couples planning a child. It is estimated that for 40% to 50% of co…

Across the Western World there is an increasing trend to postpone childbearing. Consequently, the negative influence of age on oocyte quality may lead to a difficulty in conceiving for many couples. Furthermore, lifestyle factors may exacer…

BackgroundTen per cent to 15% of couples have difficulty in conceiving. A proportion of these couples will ultimately require assisted reproduction. Prior to controlled ovarian hyperstimulation (COH) a baseline ultrasound is performed to de…

BACKGROUND: A couple may be considered to have fertility problems if they have been trying to conceive for over a year with no success. This difficulty with conception may affect up to a quarter of all couples planning a child. The reported…

ObjectivesTo compare the risk of borderline ovarian tumours in women having in vitro fertilization (IVF) with women diagnosed with infertility but not having IVF.MethodsThis was a whole-population cohort study of women aged 20-44 years seek…

ObjectivesTo examine the risk of invasive epithelial ovarian cancer in a cohort of women seeking treatment for infertility.MethodsUsing whole-population linked hospital and registry data, we conducted a cohort study of 21,646 women commenci…

INTRODUCTION: About 17% of couples in industrialised countries seek help for infertility, which may be caused by ovulatory failure, tubal damage or endometriosis, or a low sperm count. In developed countries, 80% to 90% of couples attemptin…

EDITORIAL NOTE: See https://pubmed.ncbi.nlm.nih.gov/37341141/ for a more recent review that covers this topic and has superseded this review. BACKGROUND: Endometriosis is a common gynaecological condition, characterised by the presence of e…

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To determine the effectiveness and safety of GnRHas in the treatment of the painful symptoms associated with endometriosis.

OBJECTIVE: To prospectively observe the changes occurring in endometrial glandular morphology during menstrual shedding and regeneration. DESIGN: Prospective observational study. SETTING: The academic gynaecological endoscopy unit of a univ…

BACKGROUND: Endometriomata are endometriotic deposits within the ovary. The surgical management of these blood filled cysts is controversial. The laparoscopic approach to the management of endometriomata is favoured over a laparotomy approa…

BACKGROUND: The objective of this review was to determine which is the most effective technique for treating an ovarian endometrioma; excision or ablation. METHODS: A systematic review employing the principles of the Cochrane Menstrual Diso…

Endometriosis may produce a variety of different symptoms of varying severity and lesions of variable distribution and extent. With such protean manifestations, there is confusion about how to classify the disease and how to measure the eff…

The treatment options that face a couple prior to in vitro fertilisation (IVF) depend upon the cause of their infertility. To clarify the definition of male factor subfertility to produce a pragmatic approach to treatment, Van Voorhis publi…

ABC of subfertility Unexplained infertility, endometriosis, and fibroids