Yang Chen

ORCID: 0000-0001-9406-8273 · 10 papers in corpus · active 2013-2026

Study types

  • article 5
  • other 4
  • review 1

Condition tags

  • endometriosis 6
  • irritable_bowel_syndrome 1
  • infertility 1
  • interstitial_cystitis 1
  • adenomyosis 1
article 2026
Curcumin Inhibits Fibroblast Differentiation and Epithelial-Mesenchymal Transition to Alleviate Adenomyosis through TGF-β1/Smad3 Pathway
Chinese journal of integrative medicine ·doi:10.1007/s11655-025-4215-0

OBJECTIVE: To investigate the therapeutic effects and mechanisms of curcumin (Cur) in adenomyosis (AM). METHODS: A mouse uterine AM model was established by exposing ICR neonatal mice to tamoxifen (TAM). Female neonatal mice (day 1, n=24) …

article 2025
Associations between biological aging and the risk of endometriosis: Evidence from a large population-based prospective cohort study
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2025.114595
other 2025
Mechanistic insights into endometriosis: roles of Streptococcus agalactiae and L-carnitine in lesion development and angiogenesis
Angiogenesis ·doi:10.1007/s10456-025-09991-7

Retrograde menstruation is a widely recognized etiological factor for endometriosis (EMs); however, it is not the sole cause, as not all affected women develop EMs. Emerging evidence suggests a significant association between the vaginal mi…

article 2025
Tubal occlusion in patients with hydrosalpinx modifies the uterine environment and improves in vitro fertilization outcomes within 7 months
·doi:10.1186/s13048-025-01803-2

PURPOSE: Hydrosalpinx reduces the pregnancy outcomes of in vitro fertilization and embryo transfer (IVF-ET). Tubal occlusion has been shown to improve IVF-ET success; however, the optimal timing of oocyte retrieval and the molecular changes…

other 2024
Chronic Overlapping Pain Conditions in people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): a sample from the Multi-site Clinical Assessment of ME/CFS (MCAM) study
BMC neurology ·doi:10.1186/s12883-024-03872-0

BACKGROUND: Chronic overlapping pain conditions (COPCs), pain-related conditions that frequently occur together, may occur in patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and could impact illness severity. This …

other 2024
Disease types and pathogenic mechanisms induced by PM2.5 in five human systems: An analysis using omics and human disease databases
Environment international ·doi:10.1016/j.envint.2024.108863

Atmospheric fine particulate matter (PM2.5) can harm various systems in the human body. Due to limitations in the current understanding of epidemiology and toxicology, the disease types and pathogenic mechanisms induced by PM2.5 in various …

article 2024
Ichthyosis uteri complicated by endometrial adenocarcinoma with transitional cell differentiation: A case report
·doi:10.1097/md.0000000000038792

RATIONALE: Ichthyosis uteri is a rare pathological condition characterized by the replacement of the endometrial lining by stratified squamous epithelium. Yet its occurrence with endometrial adenocarcinoma is very rare. PATIENT CONCERNS: A …

other 2023
NLRP3 inflammasome-mediated Pyroptosis induce Notch signal activation in endometriosis angiogenesis
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2023.111952

Endometriosis is characterized by the presence of endometrial tissue outside the uterus that not only causes severe pelvic pain and infertility but also increased risk for ovarian carcinogenesis in women of reproductive age. Here, we found …

article 2022
Circ_0004712 promotes endometriotic epithelial cell proliferation, migration and invasion by regulating miR-488-3p/ROCK1 axis in vitro
Reproductive biology ·doi:10.1016/j.repbio.2022.100667

Recent evidence indicates that circular RNAs (circRNAs) play crucial regulatory roles in the pathogenesis and development of endometriosis. Circ_0004712 was found to be differentially expressed in endometriosis. However, the detailed functi…

review 2013
Tumor Necrosis Factor and Interleukin‐6 Gene Polymorphisms and Endometriosis Risk in Asians: A Systematic Review and Meta‐Analysis
Annals of human genetics ·doi:10.1111/ahg.12048

A relationship between endometriosis and tumor necrosis factor (TNF-α) and interleukin-6 (IL-6) gene polymorphisms has been raised for Asians. However, this topic is controversial. This study was a meta-analysis to explore whether TNF-α/IL-…