Ichthyosis uteri complicated by endometrial adenocarcinoma with transitional cell differentiation: A case report

Liya Ding, Wangwang Liu, Hui Li, Dingpin Huang, Yang Chen, Huimin An
In: Medicine · 2024 · vol. 103(28) , pp. e38792 · doi:10.1097/md.0000000000038792 · PMID:38996162 · W4400577531
article OA: gold CC0
🔓 Open OA copy View on OpenAlex View on PubMed View at publisher

Abstract

RATIONALE: Ichthyosis uteri is a rare pathological condition characterized by the replacement of the endometrial lining by stratified squamous epithelium. Yet its occurrence with endometrial adenocarcinoma is very rare. PATIENT CONCERNS: A 68-year-old woman has been experiencing sporadic, minor vaginal hemorrhages for a few months. The gynecological evaluation revealed a uterine enlargement and imaging demonstrated an irregular mass within the uterus. DIAGNOSIS: Endometrial adenocarcinoma with transitional cell differentiation; ichthyosis uteri with dysplasia. INTERVENTIONS: Radical hysterectomy with pelvic lymphadenectomy was performed followed by postoperative radiotherapy. OUTCOMES: Postoperative follow-up at 8 months showed a favorable outcome without signs of recurrence and metastasis. LESSONS: Adequate pathological sampling is crucial to identifying the accompanying lesions of ichthyosis uteri. Finding molecular alterations in various pathological morphologies is important to understand the evolution of disease.

My notes (saved in your browser only)

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cites (1)

References (19)

SciLite annotations

chemicals 3
formaldehyde iodine leucine
organisms 1
human papillomavirus

Source provenance

openalex
last seen: 2026-06-04T00:00:01.174412+00:00
scilite
last seen: 2026-05-18T04:26:01.642840+00:00
License: CC0 · commercial use OK